146337-41-9 Usage
General Description
1-BOC-2-Azepanecarbaldehyde is a chemical compound with the molecular formula C10H17NO2. It is a carbonyl compound with a BOC-protected amine group and a seven-membered azepane ring. 1-BOC-2-AZEPANECARBALDEHYDE is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and bioactive molecules. It can undergo various chemical transformations, including reduction, oxidation, and nucleophilic addition reactions, making it a versatile intermediate in organic chemistry. Additionally, its BOC-protected amine group provides a means for selective deprotection and subsequent functionalization in organic synthesis. Overall, 1-BOC-2-Azepanecarbaldehyde plays a significant role in the development of new drugs and materials in the pharmaceutical and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 146337-41-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,3,3 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 146337-41:
(8*1)+(7*4)+(6*6)+(5*3)+(4*3)+(3*7)+(2*4)+(1*1)=129
129 % 10 = 9
So 146337-41-9 is a valid CAS Registry Number.
146337-41-9Relevant articles and documents
Studies on the aza-Claisen rearrangement of 7 to 9-membered vinylazacycles
Kim, Seok-Ho,Lee, Won-Il,Kim, Seon-Mi,Jung, Jae-Kyung,Jang, Jaebong,Sim, Jaehoon,Jung, Jong-Wha,Suh, Young-Ger
, p. 886 - 899 (2016/07/06)
A systematic study on the amide enolate-induced aza-Claisen rearrangement (ACR) of 7 to 9-membered vinylazacycles has been carried out, resulting in an efficient synthetic method to prepare 11 to 13-membered macrolactams. Key feature includes introduction of electron-donating substituents at α-position of the amide substrates possessing 7 to 9-membered vinylazacycles to facilitate amide enolate-induced ACR. In addition, substituent effects on ACR has been discussed based on the experimental results. We believe this study would provide experimental evidences for the substituent effects and envision for the synthetic application of ACR-induced ring expansion.
