147149-76-6 Usage
General Description
Nolatrexed is a potent and selective inhibitor of the enzyme thymidylate synthase, which is essential for the production of DNA. It is used in the treatment of various types of cancer, including non-small cell lung cancer and mesothelioma. Nolatrexed works by blocking the production of thymidylate, leading to DNA damage and ultimately the death of cancer cells. It is typically administered through intravenous infusion and has shown promising results in clinical trials, both as a standalone treatment and in combination with other chemotherapy drugs. However, like many chemotherapy agents, it can cause a range of side effects, including nausea, vomiting, and bone marrow suppression. Further research and clinical trials are ongoing to explore its potential in treating various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 147149-76-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,1,4 and 9 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 147149-76:
(8*1)+(7*4)+(6*7)+(5*1)+(4*4)+(3*9)+(2*7)+(1*6)=146
146 % 10 = 6
So 147149-76-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H12N4OS/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9/h2-7H,1H3,(H3,15,17,18,19)
