147201-81-8Relevant articles and documents
Synthesis and characterization of novel aminophosphine ligands based on ferrocenodecaline backbones
Weissenbacher, Max,Sturm, Thomas,Kalchhauser, Hermann,Kratky, Christoph,Weissensteiner, Walter
, p. 991 - 1009 (2002)
Novel aminophosphine ligands for enantioselective transition metal catalysts based on different ferroceno cis- and trans-decaline backbones were synthesized and structurally characterized. Their palladium dichloride complexes were tested in the asymmetric
CATHEPSIN CYSTEINE PROTEASE INHIBITORS
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Page/Page column 86, (2015/04/28)
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
Highly enantioselective desymmetrization of meso anhydrides by a bifunctional thiourea-based organocatalyst at low catalyst loadings and room temperature
Peschiulli, Aldo,Gun'ko, Yurii,Connon, Stephen J.
, p. 2454 - 2457 (2008/09/19)
(Chemical Equation Presented) Bifunctional (thio)urea-based cinchona alkaloid derivatives have been shown to promote highly efficient enantioselective desymmetrization reactions of meso anhydrides. The most selective of these catalysts is capable of the enantioselective methanolysis of succinic and glutaric anhydride derivatives to form hemiester products with >90% yield and enantiomeric excess at 1 mol % loading and ambient temperature.
