148260-92-8 Usage
Chemical class
Azetidinone compounds
Potential use
Pharmaceuticals
Properties
a. Anti-inflammatory
b. Analgesic
Potential treatment for
a. Pain
b. Inflammation
c. Other related ailments
Chemical structure features
a. Methoxyphenyl groups
b. Phenylpropyl groups
Pharmacological activities
Influenced by methoxyphenyl and phenylpropyl groups
Current status
Further research needed to understand potential therapeutic applications
Check Digit Verification of cas no
The CAS Registry Mumber 148260-92-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,2,6 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 148260-92:
(8*1)+(7*4)+(6*8)+(5*2)+(4*6)+(3*0)+(2*9)+(1*2)=138
138 % 10 = 8
So 148260-92-8 is a valid CAS Registry Number.
InChI:InChI=1/C26H27NO3/c1-29-22-15-11-20(12-16-22)25-24(10-6-9-19-7-4-3-5-8-19)26(28)27(25)21-13-17-23(30-2)18-14-21/h3-5,7-8,11-18,24-25H,6,9-10H2,1-2H3/t24-,25-/m1/s1
148260-92-8Relevant articles and documents
A simple stereoselective synthesis of the cholesterol absorption inhibitor (-)-SCH 48461
Braun, Manfred,Galle, Dietmar
, p. 819 - 820 (1996)
The cholesterol absorption inhibitor (3R,4S)-1 is synthesized in 91% ee by a stereoselective condensation of doubly deprotonated ester 2 and imine 3. The optical purity of the trans-diastereomer 1 obtained as the major isomer (trans/cis, 94:6) is enhanced to >98% ee by a single recrystallization.
Asymmetric Synthesis and Absolute Stereochemistry of Cholesterol Absorption Inhibitor, SCH 484661.
Burnett, Duane A.
, p. 7339 - 7342 (2007/10/02)
The first asymmetric synthesis of cholesterol absorption inhibitor, SCH 48461 is described.The compound was prepared from an asymmetric ester enolate-imine condensation using Oppolzer's chiral ester or the corresponding menthol ester as the stereocontroll