148687-76-7 Usage
Description
3-([3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY)-2-PHENYL-PIPERIDINE HYDROCHLORIDE, also known as L-733,060 Hydrochloride, is a chemical compound with a complex structure that features a piperidine core and a methoxy group connected to a trifluoromethylated phenyl group. It is a potent and selective NK-1 inhibitor, which makes it a valuable compound in the field of pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
3-([3,5-BIS(TRIFLUOROMETHYL)PHENYL]METHOXY)-2-PHENYL-PIPERIDINE HYDROCHLORIDE is used as an NK-1 inhibitor for the treatment of depression and nausea associated with cancer chemotherapy. Its ability to selectively inhibit the NK-1 receptor makes it a promising candidate for managing these symptoms, potentially improving the quality of life for cancer patients undergoing chemotherapy.
In the treatment of depression, L-733,060 Hydrochloride works by blocking the NK-1 receptor, which is involved in the transmission of mood-regulating signals in the brain. By inhibiting this receptor, it can help to alleviate the symptoms of depression, providing a valuable therapeutic option for patients.
For the management of nausea and vomiting, L-733,060 Hydrochloride targets the same NK-1 receptor, which plays a role in the regulation of the body's response to chemotherapy-induced emesis. By blocking this receptor, the compound can help to reduce the severity and frequency of nausea and vomiting, making the chemotherapy experience more tolerable for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 148687-76-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,6,8 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 148687-76:
(8*1)+(7*4)+(6*8)+(5*6)+(4*8)+(3*7)+(2*7)+(1*6)=187
187 % 10 = 7
So 148687-76-7 is a valid CAS Registry Number.
