149438-16-4 Usage
Molecular weight
267.27 g/mol
Structure
A formamidopyrimidine ring with a 2'-deoxyribose sugar moiety, containing two amino groups at the 2 and 5 positions, a hydroxyl group at the 4 position, and a formamido group at the 6 position.
Formation
Fapy-dA is formed by the oxidation of guanine in DNA, which can be caused by reactive oxygen species, ionizing radiation, and chemical carcinogens.
Classification
It is an oxidized derivative of 2'-deoxyadenosine.
Biological role
Fapy-dA is involved in the repair of DNA damage and has been linked to the development of various human diseases, including cancer and neurodegenerative disorders.
Research significance
Fapy-dA has been studied for its potential use as a biomarker for oxidative stress and DNA damage, and it is an important target for understanding the mechanisms of DNA damage and repair.
Check Digit Verification of cas no
The CAS Registry Mumber 149438-16-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,4,3 and 8 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 149438-16:
(8*1)+(7*4)+(6*9)+(5*4)+(4*3)+(3*8)+(2*1)+(1*6)=154
154 % 10 = 4
So 149438-16-4 is a valid CAS Registry Number.