151025-70-6 Usage
Chemical Structure
Quinoline derivative with two trifluoromethyl groups (2, 8 positions) and a cyano group (4 position)
Common Uses
Building block in organic synthesis, medicinal chemistry
Biological Activities
Studied for potential as a pharmaceutical intermediate, precursor in synthesis of bioactive compounds
Properties
High lipophilicity, chemical stability due to trifluoromethyl groups
Check Digit Verification of cas no
The CAS Registry Mumber 151025-70-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,0,2 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 151025-70:
(8*1)+(7*5)+(6*1)+(5*0)+(4*2)+(3*5)+(2*7)+(1*0)=86
86 % 10 = 6
So 151025-70-6 is a valid CAS Registry Number.
151025-70-6Relevant articles and documents
{SEQ CHAPTER h r l} Synthesis of novel trifluoromethylquinoline and bis(trifluoromethyl)quinoline derivatives
Kgokong, Joseph L.,Breytenbach, Jaco C.
, p. 100 - 103 (2007/10/03)
Six new 2- and 8-trifluoromethyl- and 2,8-bis(trifluoromethyl)quinolin-4-yl ketones were synthesised and evaluated for in vitro antimalarial activity. The ketones were prepared by condensation of the corresponding quinoline-4-carboxylic acids with pyrimidin-5-yllithium or [(1-ethyl-5-nitro-1H-imidazol-4-yl)methyl]lithium. The new compounds showed slight in vitro antimalarial activity against the chloroquine-sensitive strain of Plasmodium falciparum.
