152099-78-0 Usage
General Description
1-(2-HYDROXYETHOXY)METHYL-5-BARBITURIC ACID is a chemical compound that belongs to the barbituric acid class of drugs. It is a derivative of barbituric acid with an additional hydroxyethyl group and a methyl group attached to the nitrogen atom. 1-(2-HYDROXYETHOXY)METHYL-5-BARBITURIC ACID is likely to have sedative, hypnotic, and anti-anxiety effects, similar to other barbiturates. Barbiturates are central nervous system depressants that are used for their sedative and anesthetic properties. They have a history of medical use as sedatives and anesthetics, but their use has declined in favor of safer and more effective drugs due to their potential for abuse and overdose.
Check Digit Verification of cas no
The CAS Registry Mumber 152099-78-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,0,9 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 152099-78:
(8*1)+(7*5)+(6*2)+(5*0)+(4*9)+(3*9)+(2*7)+(1*8)=140
140 % 10 = 0
So 152099-78-0 is a valid CAS Registry Number.
152099-78-0Relevant articles and documents
Azines and azoles. CXX. Synthesis of acyclic analogs of N 1-ribosides of barbituric acid and its 5-ylidene derivatives
Studentsov,Kokhanovskii,Ganina,Nikolaeva,Fedorova,Moskvin,Ivin
, p. 261 - 265 (2004)
The reaction of 2,4,6-tris(trimethylsiloxy)pyrimidine with 2-oxabutane-1,4-diyl diacetate in methylene chloride in methylene chloride in the presence of SnCl4 proceeds regioselectively to form 1-[(2-acetoxyethoxy)methyl]barbituric acid. The latter is readily deacetylated to a free acyclic analog of N-ribosides of barbituric acid. 1-[(2-Acetoxy- and 2-hydroxyethoxy)methyl]barbituric acids easily react with aromatic and heterocyclic aldehydes in water and organic solvents, forming 5-ylidenebarbituric acids. The structure of the products was proved by 1H NMR and UV spectroscopy. Certain of the products exhibit a moderate antimicrobial and antiviral activity.
