152120-55-3

• 

• Basic information

  1. Product Name: N,N'-BIS-Z-1-GUANYLPYRAZOLE
  2. Synonyms: Benzyl ((((benzyloxy)carbonyl)aMino)(1H-pyrazol-1-yl)Methylene)carbaMate;Pyrazol(Z)2N,N'-Di-Cbz-1H-pyrazole-1-carbaMidine;N,N'-Di-Cbz-1H-pyrazole-1-carboxamidine;-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine;Pyrazol(Z)2≥ 99% (HPLC);PYRAZOLE(Z)2;N,N'-DI-Z-1H-PYRAZOL-1-CARBAMIDINE;N,N'-BIS-Z-1-GUANYLPYRAZOLE
  3. CAS NO:152120-55-3
  4. Molecular Formula: C₂₀H₁₈N₄O₄
  5. Molecular Weight: 378.38
  6. EINECS: N/A
  7. Product Categories: Guanidine Protection/Guanidinylation;Peptide Synthesis;Specialty Synthesis
  8. Mol File: 152120-55-3.mol
  9. Article Data: 3

• Chemical Properties

  1. Melting Point: 90-96 °C
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: 1.25 g/cm³
  6. Refractive Index: N/A
  7. Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
  8. Solubility: N/A
  9. PKA: 6.66±0.46(Predicted)
  10. CAS DataBase Reference: N,N'-BIS-Z-1-GUANYLPYRAZOLE(CAS DataBase Reference)
  11. NIST Chemistry Reference: N,N'-BIS-Z-1-GUANYLPYRAZOLE(152120-55-3)
  12. EPA Substance Registry System: N,N'-BIS-Z-1-GUANYLPYRAZOLE(152120-55-3)

• Safety Data

  1. Hazard Codes: Xi
  2. Statements: 36/37/38
  3. Safety Statements: 26-36
  4. WGK Germany: 3
  5. RTECS:
  6. F: 10-21
  7. HazardClass: N/A
  8. PackingGroup: N/A
  9. Hazardous Substances Data: 152120-55-3(Hazardous Substances Data)

• Suppliers
• Usage
• Well-known Company Product Price
• SDS
• Upstream product
• Downstream Products
• Article

152120-55-3 Suppliers

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• High quality N,N'-Bis-Z-1-Guanylpyrazole supplier in China

  Cas No: 152120-55-3

• No Data

• 1 Kilogram

• 30 Metric Ton/Month

• Simagchem Corporation
• Contact Supplier

• N,N'-bis-Z-1-guanylpyrazole

  Cas No: 152120-55-3

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
• Contact Supplier

• Dibenzyl [(Z)-1H-pyrazol-1-ylmethylylidene]-biscarbamate

  Cas No: 152120-55-3

• USD $ 1.2-5.0 / Kiloliter

• 5 Kiloliter

• 3000 Metric Ton/Month

• Chemwill Asia Co., Ltd.
• Contact Supplier

• N,N'-BIS-Z-1-GUANYLPYRAZOLE

  Cas No: 152120-55-3

• USD $ 1.0-10.0 / Kilogram

• 1 Kilogram

• 200 Metric Ton/Day

• Hebei Nengqian Chemical Import and Export Co., LTD
• Contact Supplier

• Wholesale price CAS 152120-55-3 with best price

  Cas No: 152120-55-3

• USD $ 139.0-210.0 / Kilogram

• 1 Kilogram

• 1000 Kilogram/Day

• Zhuozhou Wenxi import and Export Co., Ltd
• Contact Supplier

• Carbamic acid,N-[[[(phenylmethoxy)carbonyl]amino]-1H-pyrazol-1-ylmethylene]-, phenylmethylester 152120-55-3

  Cas No: 152120-55-3

• No Data

• 1 Kilogram

• 10000 Metric Ton/Month

• Shanghai Upbio Tech Co.,Ltd
• Contact Supplier

• Pyrazol(Z)2 N,N'-Bis-Z-1-Guanylpyrazole

  Cas No: 152120-55-3

• No Data

• No Data

• No Data

• Hangzhou Keyingchem Co.,Ltd
• Contact Supplier

• Pyrazol(Z)2 N,N'-Bis-Z-1-Guanylpyrazole

  Cas No: 152120-55-3

• No Data

• 10 Kilogram

• 100 Metric Ton/Month

• Wuhan Han Sheng New Material Technology Co.，Ltd
• Contact Supplier

• Carbamic acid,N-[[[(phenylmethoxy)carbonyl]amino]-1H-pyrazol-1-ylmethylene]-, phenylmethylester

  Cas No: 152120-55-3

• No Data

• No Data

• 5

• Hangzhou J&H Chemical Co., Ltd.
• Contact Supplier

• N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine

  Cas No: 152120-55-3

• No Data

• 100 Gram

• 1000 Kilogram/Month

• Henan Tianfu Chemical Co., Ltd.
• Contact Supplier

152120-55-3 Usage

Chemical Properties

Off-white powder

Uses

N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine is used as pharmaceutical intermediate.

Check Digit Verification of cas no

The CAS Registry Mumber 152120-55-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,1,2 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 152120-55:
(8*1)+(7*5)+(6*2)+(5*1)+(4*2)+(3*0)+(2*5)+(1*5)=83
83 % 10 = 3
So 152120-55-3 is a valid CAS Registry Number.

152120-55-3 Well-known Company Product Price

• Brand
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• TCI America

• (B3605)  N,N'-Bis(carbobenzoxy)-1H-pyrazole-1-carboxamidine  >98.0%(HPLC)(T)

• 152120-55-3

• 1g

• 720.00CNY

• Detail

• TCI America

• (B3605)  N,N'-Bis(carbobenzoxy)-1H-pyrazole-1-carboxamidine  >98.0%(HPLC)(T)

• 152120-55-3

• 5g

• 2,890.00CNY

• Detail

• Alfa Aesar

• (H54092)  N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine, 98+%   

• 152120-55-3

• 1g

• 733.0CNY

• Detail

• Alfa Aesar

• (H54092)  N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine, 98+%   

• 152120-55-3

• 5g

• 2930.0CNY

• Detail

• Aldrich

• (439428)  N,N′-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine  97%

• 152120-55-3

• 439428-5G

• 2,784.60CNY

• Detail

152120-55-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name	N,N'-Bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine

1.2 Other means of identification

Product number	-
Other names	N,N'-Di-Cbz-1H-pyrazole-1-carboximidamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:152120-55-3 SDS

152120-55-3Upstream product

• 152120-62-2 N-benzyloxycarbonyl-1H-pyrrazole-1-carboxamidine 
• 501-53-1 benzyl chloroformate 
• 75315-63-8 N-(benzyloxycarbonyl)succinimide 
• 152120-62-2 (N)-benzyloxycarbonyl-1H-pyrazole-1-carboxamidine 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 

152120-55-3Downstream Products

• 274901-47-2 C₂₇H₃₇N₅O₈S 
• 274901-46-1 Boc-Arg(Cbz2)-ψ[CH2SO2NH]-Gly-OEt 
• 274901-61-0 C₃₁H₄₃N₅O₁₀S 
• 468071-23-0 N^β,N^ω,N^ω'-tris(benzyloxycarbonyl)-N^ε-methyl-(S)-β-homoarginine tert-butyl ester 
• 253177-00-3 (2S,3R)-3-(1-{Benzyloxycarbonylamino-[(E)-benzyloxycarbonylimino]-methyl}-azetidin-3-ylmethyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester 
• 479622-23-6 (2S,3R)-3-(1-{Benzyloxycarbonylamino-[(E)-benzyloxycarbonylimino]-methyl}-pyrrolidin-3-ylmethyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester 
• 384830-18-6 (2S,3R)-3-(1-{Benzyloxycarbonylamino-[(E)-benzyloxycarbonylimino]-methyl}-piperidin-3-ylmethyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester 
• 384830-10-8 (2S,3R)-3-((S)-1-{Benzyloxycarbonylamino-[(E)-benzyloxycarbonylimino]-methyl}-piperidin-3-ylmethyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester 
• 384830-05-1 (2S,3R)-3-((R)-1-{Benzyloxycarbonylamino-[(E)-benzyloxycarbonylimino]-methyl}-piperidin-3-ylmethyl)-4-oxo-azetidine-2-carboxylic acid benzyl ester 
• 751476-44-5 N-[4-hydroxy-2(R)-isobutyl-3(S)-phenylpropylsuccinyl]-L-4'-[N,N'-bis(benzyloxycarbonyl)guanidinomethyl]phenylalanine N-methylamide 
• 468071-25-2 N^β,N^ω,N^ω'-tris(benzyloxycarbonyl)-N^ε-methyl-(S)-β-homoarginine 
• 468071-32-1 N^β,N^ω,N^ω'-tris(benzyloxycarbonyl)-N^ε,N^ω-dimethyl-(S)-β-homoarginine 
• 468071-29-6 N^β,N^ω,N^ω'-tris(benzyloxycarbonyl)-N^ε,N^ω-dimethyl-(S)-β-homoarginine tert-butyl ester 
• 468071-53-6 (3'S,5RS)-5-[N-[3-benzyloxycarbonylamino-6-[2,3-di(benzyloxycarbonyl)-1-methylguanidin-1-yl]hexanoyl]-N-methylamino]-5,6-dihydro-2-ureidopyrimid-4(1H)-one 

152120-55-3Relevant articles and documents

Diaminopyrimidines as P2X3 and P2X2/3 modulators

-

Page/Page column 17, (2008/12/08)

Compounds of formula (I): wherein R1 and R2 are as defined herein. Also disclosed are methods of making and using the subject compounds.

Urethane protected derivatives of 1-guanylpyrazole for the mild and efficient preparation of guanidines

Bernatowicz, Michael S.,Wu, Youling,Matsueda, Gary R.

, p. 3389 - 3392 (2007/10/02)

Bis-urethane protected derivatives of 1-guanylpyrazole were prepared and found to readily react with relatively amines at room temperature to produce bis-protected guanidines in good yields. Simultaneous removal of both protecting groups from these products efficiently produced monosubstituted guanadines.

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