1527-97-5Relevant articles and documents
The toxic aldehyde, 4-hydroxy-2-trans-nonenal (HNE) formation in natural and imitation mozzarella cheeses: Heat treatment effects
Han, In Hwa,Csallany, A. Saari
, p. 1801 - 1805 (2012)
The formation of 4-hydroxy-2-trans-nonenal (HNE), a toxic aldehyde formation, was investigated in heat treated imitation Mozzarella cheeses which are made with vegetable oils and in natural Mozzarella cheeses which contain dairy fats. The cheeses were hea
Selective reduction of carboxylic acids to aldehydes catalyzed by B(C 6F5)3
Bezier, David,Park, Sehoon,Brookhart, Maurice
, p. 496 - 499 (2013/03/29)
B(C6F5)3 efficiently catalyzes hydrosilylation of aliphatic and aromatic carboxylic acids to produce disilyl acetals under mild conditions. Catalyst loadings can be as low as 0.05 mol %, and bulky tertiary silanes are favored to give selectively the acetals. Acidic workup of the disilyl acetals results in the formation of aldehydes in good to excellent yields.
Synthesis and properties of 4,9-methanoundecafulvenes and their transformation to 3-substituted 7,12-methanocycloundeca[4,5]furo[2,3-d] pyrimidine-2,4(1H,3H)-diones: Photo-induced autorecycling oxidizing reaction toward amines
Naya, Shin-Ichi,Yamaguchi, Yohei,Nitta, Makoto
, p. 7384 - 7391 (2007/10/03)
The synthesis and properties of 4,9-methanoundecafulvene [5-(4,9-methanocycloundeca-2′,4′,6′,8′, 10′-pentaenylidene)pyrimidine-2,4,6(1,3,5H)-trione] derivatives 8a,b were studied. Their structural characteristics were investigated on the basis of the 1H and 13C NMR and UV-vis spectra. The rotational barrier (ΔG?) around the exocyclic double bond of 8a was found to be 12.55 kcal mol-1 by the variable temperature 1H NMR measurement. The electrochemical properties of 8a,b were also studied by CV measurement. Furthermore, the transformation of 8a,b to 3-substituted 7,12-methanocycloundeca[4,5]furo[2,3-d]pyrimidine-2,4(1H,3H)-diones 16a,b was accomplished by oxidative cyclization using DDQ and subsequent ring-opening and ring-closure. The structural details and chemical properties of 16a,b were clarified. Reaction of 16a with deuteride afforded C13-adduct 19 as the single product, and thus, the methano-bridge controls the nucleophilic attack to prefer endo-selectivity. The photo-induced oxidation reaction of 16a and a vinylogous compound, 3-methylcyclohepta[4,5]furo[2,3-d]pyrimidine-2,4(3H)-dione 2a, toward some amines under aerobic conditions were carried out to give the corresponding imines (isolated by converting to the corresponding 2,4-dinitrophenylhydrazones) with the recycling number of 6.1-64.0 (for 16a) and 2.7-17.2 (for 2a), respectively.