156243-64-0 Usage
Description
3,5-DIFLUORO-4-(TRIFLUOROMETHYL)BROMOBENZENE is an organic compound characterized by its aromatic ring structure, featuring two fluorine atoms at the 3rd and 5th positions, a trifluoromethyl group at the 4th position, and a bromine atom attached to the same carbon as the trifluoromethyl group. 3,5-DIFLUORO-4-(TRIFLUOROMETHYL)BROMOBENZENE is known for its unique chemical properties and reactivity, making it a valuable intermediate in the synthesis of various complex organic molecules.
Uses
Used in Pharmaceutical Industry:
3,5-DIFLUORO-4-(TRIFLUOROMETHYL)BROMOBENZENE is used as a key intermediate in the synthesis of pharmaceutical compounds, particularly those with potential applications in the treatment of various diseases. Its unique structure allows for the development of novel drugs with improved efficacy and selectivity.
Used in Chemical Synthesis:
In the field of organic chemistry, 3,5-DIFLUORO-4-(TRIFLUOROMETHYL)BROMOBENZENE is used as a versatile building block for the synthesis of a wide range of organic compounds, including those with potential applications in materials science, agrochemicals, and specialty chemicals.
Used in Lewis Acid-Promoted Synthesis:
3,5-DIFLUORO-4-(TRIFLUOROMETHYL)BROMOBENZENE is employed in the Lewis acid-promoted synthesis of unsymmetrical and highly functionalized carbazoles and dibenzofurans from biaryl triazenes. This application highlights its utility in the construction of complex molecular architectures with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 156243-64-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,2,4 and 3 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 156243-64:
(8*1)+(7*5)+(6*6)+(5*2)+(4*4)+(3*3)+(2*6)+(1*4)=130
130 % 10 = 0
So 156243-64-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H2BrF5/c8-3-1-4(9)6(5(10)2-3)7(11,12)13/h1-2H
156243-64-0Relevant articles and documents
Deoxofluorination of (Hetero)aromatic Acids
Alekseenko, Anatoliy N.,Bugera, Maksym Ya.,Gerus, Igor I.,Kiriakov, Oleksandr,Klipkov, Anton A.,Mykhailiuk, Pavel K.,Pustovit, Yurii,Razhyk, Bohdan,Semenov, Sergey,Starova, Viktoriia S.,Tananaiko, Oksana Yu.,Tarasenko, Karen,Tolmachev, Andrei A.,Trofymchuk, Serhii,Zaporozhets, Olga A.
, p. 3110 - 3124 (2020/03/23)
Diverse trifluoromethyl-substituted compounds were synthesized by deoxofluorination of cinnamic and (hetero)aromatic carboxylic acids with sulfur tetrafluoride. The obtained products were used as starting materials in the preparation of novel fluorinated amino acids, anilines, and aliphatic amines - valuable building blocks for medicinal chemistry and agrochemistry.
