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156453-52-0

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156453-52-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 156453-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,4,5 and 3 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 156453-52:
(8*1)+(7*5)+(6*6)+(5*4)+(4*5)+(3*3)+(2*5)+(1*2)=140
140 % 10 = 0
So 156453-52-0 is a valid CAS Registry Number.

156453-52-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-3-hydroxy-3-phenylpropyl 4-methylbenzenesulfonate

1.2 Other means of identification

Product number -
Other names (S)-3-hydroxy-3-phenyl-propyl 4-methyl-benzenesulfonate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:156453-52-0 SDS

156453-52-0Relevant articles and documents

Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase type 1

Xu, Zhenrong,Tice, Colin M.,Zhao, Wei,Cacatian, Salvacion,Ye, Yuan-Jie,Singh, Suresh B.,Lindblom, Peter,McKeever, Brian M.,Krosky, Paula M.,Kruk, Barbara A.,Berbaum, Jennifer,Harrison, Richard K.,Johnson, Judith A.,Bukhtiyarov, Yuri,Panemangalore, Reshma,Scott, Boyd B.,Zhao, Yi,Bruno, Joseph G.,Togias, Jennifer,Guo, Joan,Guo, Rong,Carroll, Patrick J.,McGeehan, Gerard M.,Zhuang, Linghang,He, Wei,Claremon, David A.

scheme or table, p. 6050 - 6062 (2011/10/31)

Structure based design led directly to 1,3-oxazinan-2-one 9a with an IC50 of 42 nM against 11β-HSD1 in vitro. Optimization of 9a for improved in vitro enzymatic and cellular potency afforded 25f with IC 50 values of 0.8 nM for the enzyme and 2.5 nM in adipocytes. In addition, 25f has 94% oral bioavailability in rat and >1000× selectivity over 11β-HSD2. In mice, 25f was distributed to the target tissues, liver, and adipose, and in cynomolgus monkeys a 10 mg/kg oral dose reduced cortisol production by 85% following a cortisone challenge.

Heteroarylalkyl-8-azabicyclo[3.2.1]octane compounds as mu opioid receptor antagonists

-

Page/Page column 16, (2009/04/24)

The invention provides heteroarylene substituted 8-azabicyclo[3.2.1]octane compounds of formula (I): wherein R1, R2, A, and m are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at th

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