1566-37-6Relevant articles and documents
TRIAZINE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATION THEREOF
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Page/Page column 5-6, (2008/06/13)
The invention relates to triazine derivatives of general formula (I): Wherein R1, R2 and R3 are as defined herein. The invention also relates to a method for preparing these triazine derivatives and to the therapeutic application thereof.
NEW SUBSTITUTED AZATHYMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES
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Page/Page column 43; 48, (2008/06/13)
The invention relates to substituted azathymidines and related compounds of formula (I), wherein X is N or CH, and R1, R2 and R3 are as described in the specification, processes for the preparation thereof, pharmaceutical compositions containing the same, the use thereof optionally in combination with one or more other pharmaceutically active compounds as antibacterial agents for the therapy of infective diseases, and a method for the treatment of such diseases. The compounds of formula (I) are reducing selectively the pathogenicity of bacteria within the host, but without affecting the bacteria outside the host environment.
Intramolecular Diels-Alder Reactions of 1,2,4-Triazines. Synthesis of Condensed Pyrimidines
Taylor, Edward C.,Pont, Joseph L.
, p. 4287 - 4292 (2007/10/02)
1,2,4-Triazines with C5 tethered dienophilic side chains are sterically constrained to undergo intramolecular Diels-Alder reactions across the N2/C5 triazine positions; elimination of a nitrile from the intermediate adduct (N1 and C6 of the starting 1,2,4