158493-17-5Relevant articles and documents
Stereocomplementary reductions of ring fused enelactams
Miller, Ross A.,Humphrey, Guy R.,Thompson, Andrew S.
, p. 7949 - 7952 (1995)
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Process for oxidation of steroidal compounds having allylic groups
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Example 1, (2010/01/31)
The instant invention involves a process for oxidizing compounds containing an allylic group, i.e. those containing an allylic hydrogen or allylic alcohol group, to the corresponding enones, using a ruthenium-based catalyst in the presence of a hydroperoxide. Particularly, Δ-5-steroidal alkenes can be oxidized to the corresponding Δ-5-7-keto alkenes.
Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase inhibitors with anti-bacterial, keratolytic, or anti-inflammatory agents
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, (2008/06/13)
Described is a combination method using selective inhibitors of 5α-reductase 1 and/or 2 including 7β-substituted 4-aza-5α-cholestan-3-ones and related 4-aza-5α-androstan-3-one compounds which are useful in the treatment of acne vulgaris in combination wit