159788-27-9Relevant articles and documents
Bicyclic aromatic derivatives, method for preparing them, and their use in human and veterinary medicine and in cosmetics
-
, (2008/06/13)
Bicyclic aromatic compounds, having the following formula: STR1 in which: n=0 or 1; R' represents H, OH, C1 -C4 alkoxy or C1 -C4 acyloxy; R" represents H or C1 -C4 alkoxy; or R' and R" taken together form an oxo (=O), methano (=CH2) or hydroximino (=N--OH) radical; R represents --CH2 OH or --COR7 ; R7 represents H, OR8, or STR2 R8 represents H, C1 -C4 alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl, optionally substituted, a sugar residue or STR3 where p is 1, 2 or 3 and r' and r" represent H, lower alkyl, monohydroxyalkyl, optionally interrupted by a heteroatom, polyhydroxyalkyl, optionally substituted aryl or benzyl, an amino acid residue or an aminated sugar residue or taken together with the nitrogen atom to which they are attached form a heterocycle; A represents methylene or dimethylene, substituted or not with lower alkyl, R1, R2, R3 and R4 represent H or lower alkyl, R1 and R3 taken together are capable of forming a methylene or dimethylene radical, when A represents dimethylene; R5 and R6 represent H or methyl, and the salts of said compounds, as well as their optical and geometric isomers. This active compound is employed in pharmaceutical or cosmetic preparations.
