1607-57-4Relevant articles and documents
Bromination of Tetraphenylethane and Triphenylethane
Smith, William B.
, p. 187 - 189 (1981)
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Esterase-activated aggregation-induced emission type anticancer prodrug and preparation method thereof
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Paragraph 0036-0038, (2020/07/28)
The invention discloses an esterase activated aggregation-induced emission type anticancer prodrug and a preparation method thereof. The structural general formula of the prodrug is shown in the specification, wherein Drub represents carboxyl-lost chlorambucil, methotrexate and the like, and the prodrug is obtained by taking a tetraphenyl ethylene derivative and methylquinoline as raw materials toobtain aggregation-induced emission molecules and esterifying the aggregation-induced emission molecules with an anti-cancer drug. The prodrug disclosed by the invention has the characteristic of activating and lightening esterase; on one hand, aggregation-induced emission molecules released under the action of esterase in vivo have a relatively high specific marking function on cancer cells; onthe other hand, released aggregation-induced emission molecules have high singlet oxygen generation capacity, and chemotherapy and phototherapy are combined, so that the aggregation-induced emission molecules have wide application prospects.
Pyridine-cored V-shaped π-conjugated oligomers: Synthesis and optical properties
Jana, Debabrata,Ghorai, Binay K.
experimental part, p. 7309 - 7316 (2012/09/22)
A new series of V-shaped pyridine-cored π-conjugated oligomers are synthesized utilizing two-fold Heck/Suzuki coupling reactions. Optical properties of these compounds (λmax=390-449 nm, Φfl=79-5%, in solutions) are discussed. They are shown to be thermally stable and soluble in common organic solvents. Stilbenoid oligomers exhibited much higher fluorescence quantum yields than tri- and tetra-phenylethylene substituted oligomers in solutions.
