16163-48-7 Usage
General Description
1-Amino-4-methyl-1H-imidazole-2-thiol, also known as methimazole, is a chemical compound with the molecular formula C4H6N2S. It is a thioamide derivative and is primarily used as an antithyroid medication to treat hyperthyroidism by inhibiting the production of thyroid hormones. Methimazole works by blocking the activity of an enzyme known as thyroid peroxidase, which is involved in the synthesis of thyroid hormones. It is typically administered orally and has a relatively long duration of action, making it suitable for once-daily dosing. Methimazole is generally well-tolerated, but it can cause side effects such as skin rashes, liver toxicity, and suppression of white blood cells in some individuals. It is important to use methimazole under the guidance of a healthcare professional and to undergo regular monitoring of thyroid function and blood cell counts while taking the medication.
Check Digit Verification of cas no
The CAS Registry Mumber 16163-48-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,6 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16163-48:
(7*1)+(6*6)+(5*1)+(4*6)+(3*3)+(2*4)+(1*8)=97
97 % 10 = 7
So 16163-48-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H7N3S/c1-3-2-7(5)4(8)6-3/h2H,5H2,1H3,(H,6,8)
16163-48-7Relevant articles and documents
FUSED HETEROCYCLIC COMPOUND AND USE THEREOF
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Page/Page column 210, (2008/06/13)
The present invention relates to wherein each symbol is as defined in the specification. The compound has a superior mineral corticoidreceptorantagonistic action and is useful as an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like, a compound having a fused heterocycle, or a prodrug thereof, or a salt thereof; and an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like.