161691-23-2Relevant articles and documents
An asymmetric approach to the pyrrolizidine ring system via N-acetyl and N-propionyl anion cyclisation processes
Murray,Murray, Anthony,Proctor,Proctor, George R.,Murray,Murray, P. John
, p. 291 - 294 (1995)
An efficient route to the pyrrolizidine ring system has been developed. The method, which uses N-acetyl and N-propionyl anion cyclisation reactions as the key steps has provided the natural pyrrolizidines (-)-(1R, 8S)-1-hydroxypyrrolizidine (10), (-)-pyrrolizidin-1-ene-3-one (13), (±)-trachelanthamidine (18) together with a range of 2-methyl substituted pyrrolizidine-3-ones.
Intramolecular Wittig reaction: A new synthesis of (S)-pyrrolam A
Majik, Mahesh S.,Parameswaran, Perunninakulath S.,Tilve, Santosh G.
experimental part, p. 1500 - 1504 (2009/02/07)
A straightforward synthesis of (S)-pyrrolam A is described. The synthesis involves in situ generation of the phosphorane 3, followed by an intramolecular Wittig reaction to furnish (S)-pyrrolam A.
A short synthesis of (S)-pyrrolam a via domino oxidation-Wittig reaction
Majik, Mahesh S.,Shet, Jyoti,Tilve, Santosh G.,Parameswaran
, p. 663 - 665 (2008/01/08)
A short synthesis of (S)-pyrrolam A starting from readily available N-(benzyloxycarbonyl)-L-prolinol is described that makes use of a domino primary alcohol oxidation-Wittig reaction as the key step. Georg Thieme Verlag Stuttgart.