1619-57-4Relevant articles and documents
Diastereoselective Synthesis of Phycocyanobilin-Cysteine Adducts
Bishop, John E.,Nagy, Jon O.,O'Connell, John F.,Rapoport, Henry
, p. 8024 - 8035 (1991)
Methodology is presented for the synthesis of two diastereomers of a cysteine-linked phycocyanobilin derivative. The crucial reaction is a diastereoselective 1,6-Michael addition of cysteine methyl ester to an appropriate dihydropyrromethenone educt. The diastereomers so generated were then elaborated to two phycocyanobilin trimethyl esters. Definitive assignments of relative stereochemistry, double bond geometry, and solution conformation are accomplished by application of ROESY NMR experiments, while absolute stereochemical assignments are based on degradation to compounds of known chirality.
Kurts et al.
, p. 4759,4764 (1971)
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Guibe,Sarthou,Bram
, p. 3139 - 3151 (1974)
The alkylation of alkali metal and N+Bu4 ethylacetoacetate enolates by means of ethyl iodide, bromide and tosylate has been studied in dimethoxyethane, in order to measure the reactivity of the associated forms. C/O alkylation ratios
Synthesis of enantiomerically enriched α,α-disubstituted β,γ-epoxy esters using hydrolytic kinetic resolution catalyzed by salenCo(III)
Viera, Ignacio,Manta, Eduardo,Gonzalez, Lucia,Mahler, Graciela
experimental part, p. 631 - 635 (2010/08/03)
Novel α,α-disubstituted epoxy esters were prepared in enantiopure form by hydrolytic kinetic resolution (HKR) of the corresponding racemic mixtures using chiral salenCo(III) as catalyst. The methodology provides a convenient route to enantioenriched β,γ-epoxy esters 2a, 2c and 2d.
The efficiency of diphenylalkylsulfonium salts as alkylating agents
Badet, Bernard,Julia, Marc,Lefebvre, Christian
, p. 431 - 434 (2007/10/02)
A series of the title reagents have been used for the alkylation of a number of nucleophiles including iodide, cyanide, thiocyanate and fluoride ions as well as ethyl acetoacetate, phenylacetonitrile and a variety of nitrogen heterocyclic compounds.The results compared favorably with literature methods.
