163265-38-1 Usage
Description
DABCYL-ARG-GLY-VAL-VAL-ASN-ALA-SER-SER-ARG-LEU-ALA-EDANS is a synthetic peptide composed of a sequence of amino acids, including arginine (ARG), glycine (GLY), valine (VAL), asparagine (ASN), alanine (ALA), and serine (SER), with an EDANS fluorophore and a DABCYL quencher molecule attached. This peptide is designed for use in fluorescence resonance energy transfer (FRET) assays, where the DABCYL quencher can suppress the fluorescence of the EDANS fluorophore when in close proximity. This property allows for the measurement of changes in fluorescence intensity, which can be indicative of protein-protein interactions or enzymatic activity. The specific sequence of amino acids in this peptide may have been engineered for a particular biological or analytical application, such as investigating enzyme activity or protein binding affinities.
Uses
Used in Biochemical Research:
DABCYL-ARG-GLY-VAL-VAL-ASN-ALA-SER-SER-ARG-LEU-ALA-EDANS is used as a fluorescent probe for studying protein-protein interactions and enzymatic activity in biochemical research. The fluorescence resonance energy transfer (FRET) between the EDANS fluorophore and the DABCYL quencher allows researchers to monitor changes in fluorescence intensity, providing insights into molecular interactions and enzymatic processes.
Used in Drug Development:
In the pharmaceutical industry, DABCYL-ARG-GLY-VAL-VAL-ASN-ALA-SER-SER-ARG-LEU-ALA-EDANS can be utilized as a tool for high-throughput screening of potential drug candidates. The peptide's fluorescence properties can be employed to assess the binding affinity of drug molecules to target proteins, aiding in the discovery of new therapeutic agents.
Used in Diagnostic Assays:
DABCYL-ARG-GLY-VAL-VAL-ASN-ALA-SER-SER-ARG-LEU-ALA-EDANS can be incorporated into diagnostic assays to detect specific proteins or enzymatic activities. The change in fluorescence intensity upon interaction with the target molecule can serve as a signal for the presence or activity of the analyte of interest, enabling the development of sensitive and specific diagnostic tools.
Used in Environmental Monitoring:
This peptide can also be applied in environmental monitoring, where it may be used to detect the presence of specific contaminants or to study the effects of pollutants on protein function. The fluorescence properties of DABCYL-ARG-GLY-VAL-VAL-ASN-ALA-SER-SER-ARG-LEU-ALA-EDANS can provide a sensitive and quantitative measure of environmental impacts on biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 163265-38-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,3,2,6 and 5 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 163265-38:
(8*1)+(7*6)+(6*3)+(5*2)+(4*6)+(3*5)+(2*3)+(1*8)=131
131 % 10 = 1
So 163265-38-1 is a valid CAS Registry Number.
