16499-53-9 Usage
Description
3-IODO-4-NITROBENZOTRIFLUORIDE, with the molecular formula C7H3F3INO2, is a chemical compound that serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. Its unique structure, featuring both iodo and nitro functional groups, allows it to react with a variety of organic compounds, making it a valuable precursor for the preparation of other organic compounds. However, due to its high reactivity and potential hazards, it requires careful handling to prevent irritation to the skin, eyes, and respiratory system, as well as to avoid harm from swallowing or inhalation.
Uses
Used in Pharmaceutical Industry:
3-IODO-4-NITROBENZOTRIFLUORIDE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its ability to react with different organic compounds makes it a valuable precursor in the development of new drugs and medications.
Used in Agrochemical Industry:
3-IODO-4-NITROBENZOTRIFLUORIDE is used as a chemical intermediate in the production of agrochemicals. Its versatility in reacting with organic compounds contributes to the development of effective pesticides, herbicides, and other agricultural chemicals.
Used in Organic Synthesis:
3-IODO-4-NITROBENZOTRIFLUORIDE is used as a versatile reagent in organic synthesis for the preparation of other organic compounds. Its presence of both iodo and nitro functional groups allows for a wide range of reactions, making it a useful building block in the synthesis of complex organic molecules.
Safety Precautions:
Due to its high reactivity and potential hazards, 3-IODO-4-NITROBENZOTRIFLUORIDE should be handled with caution. It can cause irritation to the skin, eyes, and respiratory system, and may be harmful if swallowed or inhaled. Proper safety protocols, including appropriate storage and handling procedures, should be followed to minimize risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 16499-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,4,9 and 9 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16499-53:
(7*1)+(6*6)+(5*4)+(4*9)+(3*9)+(2*5)+(1*3)=139
139 % 10 = 9
So 16499-53-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H3F3INO2/c8-7(9,10)4-1-2-6(12(13)14)5(11)3-4/h1-3H
16499-53-9Relevant articles and documents
Au-catalyzed formation of functionalized quinolines from 2-alkynyl arylazide derivatives
Gronnier, Colombe,Boissonnat, Guillaume,Gagosz, Fabien
supporting information, p. 4234 - 4237 (2013/09/12)
A new method for converting 2-alkynyl arylazide derivatives into functionalized polysubstituted quinolines following a gold-catalyzed 1,3-acetoxy shift/cyclization/1,2-group shift sequence has been developed. This transformation proceeds under mild reaction conditions, is efficient, and tolerates a large variety of functional groups.
