166374-49-8 Usage
General Description
The chemical compound "(1S,2R,3S,4S,6S)-8-[3-Oxatricyclo[3.2.1.0(2,4)]oct-6-yl]-1,3-dipropylxanthine" is a derivative of xanthine. It is a purine alkaloid that acts as a potent and selective antagonist of adenosine receptors. (1S,2R,3S,4S,6S)-8-[3-Oxatricyclo[3.2.1.0(2,4)]oct-6-yl]-1,3-dipropylxanthine has been studied for its potential pharmaceutical applications, particularly in the treatment of neurological and cardiovascular disorders. It is known to have a high affinity for the A1 and A2A adenosine receptors, and its specific pharmacological properties make it a promising candidate for the development of novel therapeutic agents. Additionally, its structural complexity and unique properties have attracted interest from researchers in the field of organic chemistry for the synthesis of related compounds with improved pharmacological profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 166374-49-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,3,7 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 166374-49:
(8*1)+(7*6)+(6*6)+(5*3)+(4*7)+(3*4)+(2*4)+(1*9)=158
158 % 10 = 8
So 166374-49-8 is a valid CAS Registry Number.
166374-49-8Relevant articles and documents
Synthesis of an o-nitrobenzyl attached A1 adenosine receptor antagonist, a prodrug approach
Chang, HeXi,Ensinger, Carol,McCargar, Robert D.,Vittimberga, Bruno M.
, p. 2605 - 2611 (2007/10/03)
The o-nitrobenzyl group, possessing distinct advantage of being photolabile under mild conditions, was successfully connected to 8-(5,6-epoxynorbornan-2-yl)-1,3-dipropylxanthine (5), a high specific A1 adenosine receptor antagonist. The resulting compound 4 would have potential use as a prodrug.
