166438-65-9 Usage
General Description
1-(4-Methanesulfonyl-phenyl)-piperidin-4-ol, also known as Suvorexant, is a chemical compound used as a medication to treat insomnia. It belongs to the class of drugs called orexin receptor antagonists, which work by blocking the action of orexin, a neurotransmitter that regulates wakefulness and arousal. Suvorexant is a central nervous system depressant and is typically prescribed for short-term use in people who have trouble falling asleep or staying asleep. It is available in tablet form and is taken orally. Common side effects of Suvorexant may include daytime drowsiness, headaches, and dizziness. It is important to use this medication as directed by a healthcare professional to minimize the risk of side effects and potential drug interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 166438-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,4,3 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 166438-65:
(8*1)+(7*6)+(6*6)+(5*4)+(4*3)+(3*8)+(2*6)+(1*5)=159
159 % 10 = 9
So 166438-65-9 is a valid CAS Registry Number.
166438-65-9Relevant articles and documents
Nickel-Catalyzed Amination of (Hetero)aryl Halides Facilitated by a Catalytic Pyridinium Additive
Han, Dongyang,Li, Sasa,Xia, Siqi,Su, Mincong,Jin, Jian
supporting information, p. 12349 - 12354 (2020/09/09)
An efficient and operationally simple Ni-catalyzed amination protocol has been developed. This methodology features a simple NiII salt, an organic base and catalytic amounts of both a pyridinium additive and Zn metal. A diverse number of (hetero)aryl halides were coupled successfully with primary and secondary alkyl amines, and anilines in good to excellent yields. Similarly, benzophenone imine gave the corresponding N-arylation product in an excellent yield.
