166977-43-1

• 

• Basic information

  1. Product Name: BMS453
  2. Synonyms: BMS453;4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid;(E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid
  3. CAS NO:166977-43-1
  4. Molecular Formula: C27H24O2
  5. Molecular Weight: 380.47826
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 166977-43-1.mol
  9. Article Data: 0

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: white to beige/
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: Store at -20°C
  8. Solubility: DMSO: soluble10mg/mL, clear
  9. CAS DataBase Reference: BMS453(CAS DataBase Reference)
  10. NIST Chemistry Reference: BMS453(166977-43-1)
  11. EPA Substance Registry System: BMS453(166977-43-1)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 166977-43-1(Hazardous Substances Data)

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166977-43-1 Suppliers

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• (E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid

  Cas No: 166977-43-1

• No Data

• 10 Milligram

• Amadis Chemical Co., Ltd.
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• Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-

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• Kono Chem Co.,Ltd
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• BMS453 CAS No.166977-43-1

  Cas No: 166977-43-1

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• Guangdong Juda Chemical Industrial Co.,Limited
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• BMS 453

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• BOC Sciences
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• BMS453

  Cas No: 166977-43-1

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• 1 Milligram

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• Xiamen Jenny Chemical Technology Co., Ltd.
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• BMS453

  Cas No: 166977-43-1

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• 1-100 Metric Ton/Day

• ZHEJIANG JIUZHOU CHEM CO.,LTD
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• BMS-189453,166977-43-1

  Cas No: 166977-43-1

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• 1 Gram

• 10 Kilogram/Month

• Wuhan MoonZY Biological Technology Co.,Ltd
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• BMS 453;4-[(1E)-2-(5,6-Dihydro-5,5-diMethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid

  Cas No: 166977-43-1

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• Wuxi Morality Chemical Co., Ltd
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• BMS453 supplier with competitive price in stock-Rechems

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• Shanghai Rechem Science Co., Ltd.
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166977-43-1 Usage

Description

BMS453 is a synthetic retinoid and RARβ antagonist that also exhibits antagonist activity in RARα.

Uses

Used in Pharmaceutical Industry:
BMS453 is used as a therapeutic agent for the treatment of various diseases and conditions. Its antagonist activity in RARα and RARβ makes it a potential candidate for targeting specific signaling pathways and modulating gene expression, which can be beneficial in treating certain types of cancer and other disorders.
Used in Cancer Research:
BMS453 is used as a research tool for studying the role of retinoid receptors in cancer development and progression. Its antagonist activity in RARα and RARβ allows researchers to investigate the underlying mechanisms of these receptors in different types of cancer, potentially leading to the discovery of new therapeutic targets and treatment strategies.
Used in Drug Development:
BMS453 is used as a lead compound in the development of new drugs targeting retinoid receptors. Its antagonist activity in RARα and RARβ can be further optimized and modified to create more potent and selective drugs for the treatment of various diseases, including cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 166977-43-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,9,7 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 166977-43:
(8*1)+(7*6)+(6*6)+(5*9)+(4*7)+(3*7)+(2*4)+(1*3)=191
191 % 10 = 1
So 166977-43-1 is a valid CAS Registry Number.

166977-43-1 Well-known Company Product Price

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• Sigma

• (SML1149)  BMS-189453  ≥98% (HPLC)

• 166977-43-1

• SML1149-5MG

• 1,107.99CNY

• Detail

• Sigma

• (SML1149)  BMS-189453  ≥98% (HPLC)

• 166977-43-1

• SML1149-25MG

• 4,469.40CNY

• Detail

166977-43-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	4-[(E)-2-(5,5-Dimethyl-8-phenyl-5,6-dihydro-2-naphthalenyl)vinyl] benzoic acid

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:166977-43-1 SDS

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