16703-48-3 Usage
General Description
2-(Dimethylamino)-2-thioxoacetic acid ethyl ester is a chemical compound with the molecular formula C6H11NO2S. It is an ethyl ester derivative of 2-(dimethylamino)-2-thioxoacetic acid, and it is commonly used as a reagent in organic synthesis and chemical research. 2-(Dimethylamino)-2-thioxoacetic acid ethyl ester is a white or off-white solid that is soluble in organic solvents. It is known for its ability to react with various nucleophiles and electrophiles, making it a versatile building block for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it has been investigated as a potential precursor for the preparation of new classes of bioactive compounds. Due to its potent chemical properties, careful handling and proper safety precautions are required when working with 2-(dimethylamino)-2-thioxoacetic acid ethyl ester.
Check Digit Verification of cas no
The CAS Registry Mumber 16703-48-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,7,0 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16703-48:
(7*1)+(6*6)+(5*7)+(4*0)+(3*3)+(2*4)+(1*8)=103
103 % 10 = 3
So 16703-48-3 is a valid CAS Registry Number.
16703-48-3Relevant articles and documents
Efficient Synthesis of α-Ketothioamides From α-Nitroketones, Amines or DMF and Elemental Sulfur Under Oxidant-Free Conditions
Zhang, Zhenlei,Yang, Jiusi,Yu, Renjie,Wu, Kairui,Bu, Jiping,Li, Shaoke,Qian, Peng,Sheng, Liangquan
supporting information, p. 5209 - 5212 (2021/10/19)
We have developed a practical, general protocol for denitration of readily available α-nitroketones with sulfur and amines to access a broad range of α-ketothioamides under mild conditions. Such a reaction proceeds under metal-, oxidant-, and catalyst-free conditions to provide synthetically useful α-ketothioamides. Furthermore, the mild reaction conditions tolerate a wide range of substrates especially for the synthesis of aliphatic α-ketothioamides which are rarely reported.
