16843-68-8 Usage
Description
(4E,4aS)-4-Ethylidene-4,4a,5,6-tetrahydro-1α-hydroxy-7,16-dimethyl-1H,3H,7H-6β,11cβ-(epoxymethano)-6aα,11bα-(iminoethano)pyrano[4,3-c]carbazol-12-one is a minor constituent derived from the alkaloidal extract of Hunteria urnbellata (K Schum) Stapf. It forms colorless crystals when purified from propanol and exhibits strong levorotation with [α]D 243°. The compound features two methylimino groups, a hydroxyl group, and a lactone ring. Its original structure has been revised based on NMR and mass spectra analysis.
Uses
Used in Pharmaceutical Industry:
(4E,4aS)-4-Ethylidene-4,4a,5,6-tetrahydro-1α-hydroxy-7,16-dimethyl-1H,3H,7H-6β,11cβ-(epoxymethano)-6aα,11bα-(iminoethano)pyrano[4,3-c]carbazol-12-one is used as a potential pharmaceutical candidate for various applications due to its unique chemical structure and properties. The presence of two methylimino groups, a hydroxyl group, and a lactone ring may contribute to its potential therapeutic effects.
Used in Chemical Research:
(4E,4aS)-4-Ethylidene-4,4a,5,6-tetrahydro-1α-hydroxy-7,16-dimethyl-1H,3H,7H-6β,11cβ-(epoxymethano)-6aα,11bα-(iminoethano)pyrano[4,3-c]carbazol-12-one is also used in chemical research for studying the structure-activity relationships of similar compounds and understanding their potential applications in various fields, such as drug discovery and development.
Used in Analytical Chemistry:
(4E,4aS)-4-Ethylidene-4,4a,5,6-tetrahydro-1α-hydroxy-7,16-dimethyl-1H,3H,7H-6β,11cβ-(epoxymethano)-6aα,11bα-(iminoethano)pyrano[4,3-c]carbazol-12-one can be employed as a reference compound in analytical chemistry for the development and validation of analytical methods, such as chromatography and mass spectrometry, for the separation and identification of complex mixtures.
References
Bevan et al., Chern. Ind., 603 (1965)
Revised structure:
Bevan et al., Tetrahedron, 23,3809 (1967)
Check Digit Verification of cas no
The CAS Registry Mumber 16843-68-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,4 and 3 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 16843-68:
(7*1)+(6*6)+(5*8)+(4*4)+(3*3)+(2*6)+(1*8)=128
128 % 10 = 8
So 16843-68-8 is a valid CAS Registry Number.
16843-68-8Relevant articles and documents
Alcaloides des feuilles, ecorces de tronc, ecorces de racines et graines d'Hunteria congolana
Vercauteren, Joseph,Massiot, Georges,Men-Olivier, Louisette Le,Levy, Jean,Delaude, Clement
, p. 291 - 296 (2007/10/02)
Twenty-three alkaloids have been isolated from the leaves, root bark, stem bark and seeds of Hunteria congolana Pichon; among these, nine are novel alkaloids.They are: akuammicine, 17-hydroxypseudoakuammigine, 17-methoxypseudo-akuammigine, corymine, acetylcorymine, desformocorymine, 3-epidihydrocorymine-3-acetate, 3-epidihydrocorymine diacetate, 3-epidihydrocorymine, eburnamenine, eburnamine, eburnamonine, eripinal, isoeburnamine, lanceomigine, norisocorymine, noreripinal, pleiocarpamine, 2,7-dihydropleiocarpamine, pleiomutinine, 19'-epipleiomutinine, umbellamine and vincadifformine (novel alcaloids are underlined).The structures of the novel alkaloids have been established by spectroscopic means and by chemical correlations with known compounds.
