17264-88-9Relevant articles and documents
Designing of homo and heteroleptic zinc(II) carboxylates: synthesis, spectroscopic characterizations, DNA binding study, CTAB interaction and in vitro antimicrobial evaluations
Ullah, Kaleem,Sirajuddin, Muhammad,Zubair, Muhammad,Haider, Ali,Ali, Saqib,Ullah, Faizan,Dutkiewicz, Grzegorz,Kubicki, Maciej,Rizzoli, Corrado
, p. 1163 - 1177 (2019)
Synthesis of two homoleptic and five heteroleptic zinc (II) carboxylate complexes with two different ligands: HL1 = 3-chlorobenzoic acid and HL2 = 2-(4-chlorophenyl) acetic acid have been reported in this paper. The general formulae of the two homoleptic complexes are: Zn(L1)2(1), and Zn(L2)2(2). Similarly, the general formulae for two different types of heteroleptic complexes are: (Type-I): [(Zn)2(L1)4(bipy)2(H2O)] (3), [Zn(L2)2(bipy)(H2O)] (4) and (Type-II): [ZnL1L2] (5), [ZnL1L2(py)] (6) and [ZnL1L2(bipy)] (7). The synthesized complexes were characterized in the solid state by FT-IR, CHN analyses and in solution state by NMR (1H, 13C) spectroscopy. Complexes 3 and 4 were also characterized by single crystal analysis where data revealed that the geometry around each Zn atom is distorted trigonal bipyramidal and octahedral, respectively. The synthesized complexes were interacted with SS-DNA and CTAB (surfactant). Interaction of the synthesized compounds with SS-DNA was studied by UV–visible spectroscopy and viscometry and intercalative mode of interaction was exhibited. Moreover, the interaction of the synthesized complexes with CTAB was studied by conductometry showing a strong binding that is evident from higher CMC and negative Gibbs free energy of micellization (ΔGm) values. The tested compounds were further screened for in vitro antibacterial and antifungal activities and were found active against the studied strains of bacteria and fungus.
Studies of the Borderline between Concerted and Stepwise Mechanisms of Elimination : E1cB Elimination of Fluoren-9-ylmethyl Carboxylate Esters
O'Ferrall, Rory A. More,Larkin, Finbar,Walsh, Peter
, p. 1573 - 1580 (2007/10/02)
Rates of β-elimination of carboxylate leaving groups from fluoren-9-ylmethyl carboxylate esters in methanolic sodium methoxide at 25 deg C are reported.An E1cB mechanism with rate-determining formation of a carbanion intermediate is assigned on the basis of near identity of measured elimination rates and rates of carbanion formation predicted from a Taft correlation, and the similarity with elimination of 1-(1-acetoxy-1-methylethyl)indene for which the mechanism has been established by Ahlberg and Thibblin.Values of ρ=0.42 and βlg=0.27 measured for substituted benzoate leaving groups are a little larger than expected (ca. 0.24 and 0.18, respectively) and the discrepancy is tentatively ascribed to conformational enhancement of remote substituent effects, rather than to a contribution of E2 elimination.The effects of alkyl and aryl substitution α to the leaving group are discussed, especially in relation to the borderline between concerted and stepwise mechanisms.The measurements fail to confirm an earlier inference that the borderline shows a discontinuity in transition-state structure at the point of mechanistic change.