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1736-74-9

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1736-74-9 Usage

Chemical Properties

clear light pink liquid

Uses

Different sources of media describe the Uses of 1736-74-9 differently. You can refer to the following data:
1. 4-(Trifluoromethoxy)benzyl alcohol is used in biological processes as substrate specificity of inducible O-demethylase of Sporomusa ovata for methoxynaphthols, methoxyfuran and fluoroanisols under anaerobic conditions.
2. 4-(Trifluoromethoxy)benzyl alcohol may be used in chemical synthesis.

General Description

4-(Trifluoromethoxy)benzyl alcohol is an organic building block.

Check Digit Verification of cas no

The CAS Registry Mumber 1736-74-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,3 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1736-74:
(6*1)+(5*7)+(4*3)+(3*6)+(2*7)+(1*4)=89
89 % 10 = 9
So 1736-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H7F3O2/c9-8(10,11)13-7-3-1-6(5-12)2-4-7/h1-4,12H,5H2

1736-74-9 Well-known Company Product Price

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  • (Code)Product description
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  • Alfa Aesar

  • (A19250)  4-(Trifluoromethoxy)benzyl alcohol, 97%   

  • 1736-74-9

  • 1g

  • 479.0CNY

  • Detail
  • Alfa Aesar

  • (A19250)  4-(Trifluoromethoxy)benzyl alcohol, 97%   

  • 1736-74-9

  • 5g

  • 1032.0CNY

  • Detail

1736-74-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(Trifluoromethoxy)benzyl alcohol

1.2 Other means of identification

Product number -
Other names 4-(Trifluoromethoxy)benzyl Alcohol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1736-74-9 SDS

1736-74-9Relevant articles and documents

ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND

-

, (2021/10/22)

The present invention relates to an isoindoline compound as represented by general formula (I) and used as a CRBN regulator, and a preparation method, a pharmaceutical composition, and an application of the isoindoline compound. Specifically, a class of polysubstituted isoindoline compound provided in the present invention, as a class of CRL4CRBN E3 ubiquitin ligase regulator having a novel structure, has good anti-tumor activity and immunoregulatory activity, and can be used for preparing drugs for treating diseases associated with a CRL4CRBN E3 ubiquitin ligase.

The Stereoselective Oxidation of para-Substituted Benzenes by a Cytochrome P450 Biocatalyst

Chao, Rebecca R.,Lau, Ian C.-K.,Coleman, Tom,Churchman, Luke R.,Child, Stella A.,Lee, Joel H. Z.,Bruning, John B.,De Voss, James J.,Bell, Stephen G.

supporting information, p. 14765 - 14777 (2021/09/14)

The serine 244 to aspartate (S244D) variant of the cytochrome P450 enzyme CYP199A4 was used to expand its substrate range beyond benzoic acids. Substrates, in which the carboxylate group of the benzoic acid moiety is replaced were oxidised with high activity by the S244D mutant (product formation rates >60 nmol.(nmol-CYP)?1.min?1) and with total turnover numbers of up to 20,000. Ethyl α-hydroxylation was more rapid than methyl oxidation, styrene epoxidation and S-oxidation. The S244D mutant catalysed the ethyl hydroxylation, epoxidation and sulfoxidation reactions with an excess of one stereoisomer (in some instances up to >98 %). The crystal structure of 4-methoxybenzoic acid-bound CYP199A4 S244D showed that the active site architecture and the substrate orientation were similar to that of the WT enzyme. Overall, this work demonstrates that CYP199A4 can catalyse the stereoselective hydroxylation, epoxidation or sulfoxidation of substituted benzene substrates under mild conditions resulting in more sustainable transformations using this heme monooxygenase enzyme.

A method of synthesis of primary alcohol (by machine translation)

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Paragraph 0099; 0100; 0101; 0102; 0103, (2019/03/17)

The invention discloses a method for synthesizing a primary alcohol, using transition metal catalysis, the use of isopropanol as a hydrogen source to synthesize primary alcohol, the reaction not only using a cheap, environmental protection of isopropanol as a hydrogen source and solvent, and has high yield, environmental protection and the like, so that the reaction has broad prospects for development. (by machine translation)

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