1738-76-7Relevant articles and documents
Rhenium complexes of bidentate, bis-bidentate and tridentate N-heterocyclic carbene ligands
Chan, Chung Ying,Barnard, Peter J.
, p. 19126 - 19140 (2015)
A series of eight Rhenium(i)-N-heterocyclic carbene (NHC) complexes of the general form [ReCl(CO)3(C^C)] (where C^C is a bis(NHC) bidentate ligand), [ReCl(CO)3(C^C)]2 (where C^C is a bis-bidentate tetra-NHC ligand) and [Re(CO)3(C^N^C)]+[X]- (where C^N^C is a bis(NHC)-amine ligand and the counter ion X is either the ReO4- or PF6-) have been synthesised using a Ag2O transmetallation protocol. The novel precursor imidazolium salts and Re(i) complexes were characterized by elemental analysis, 1H and 13C NMR spectroscopy and the molecular structures for two imidazolium salt and six Re(i) complexes were determined by single crystal X-ray diffraction. These NHC ligand systems are of interest for possible applications in the development of Tc-99m or Re-186/188 radiopharmaceuticals and as such the stability of two complexes of the form [ReCl(CO)3(C^C)] and [Re(CO)3(C^N^C)][ReO4] were evaluated in ligand challenge experiments using the metal binding amino acids l-histidine or l-cysteine. These studies showed that the former was unstable, with the chloride ligand being replaced by either cysteine or histidine, while no evidence for transchelation was observed for the latter suggesting that bis(NHC)-amine ligands of this type may be suitable for biological applications.
Synthesis of novel all-cis-functionalized cyclopropane template-assembled collagen models
Yamazaki,Sakamoto,Suzuri,Doi,Nakazawa,Kobayashi
, p. 1870 - 1875 (2001)
An all-cis-functionalized cyclopropane template to connect the three peptide chains in a collagen model is designed. Stereoselective synthesis of cyclopropane-assembled collagen-model 2b with the minimum unit of Gly-Pro-Pro is based on a novel 1-seleno-2-silylethene [2 + 1] cycloaddition strategy. Reaction of the 1-seleno-2-silylethene 4 with triester-substituted olefin 5 in the presence of ZnI2 gives [2 + 1] cycloadduct 6 stereoselectively. Cyclopropane 6 is selectively transformed into triol 10 in four steps. The reaction of 10 and three equivalents ofN-Boc-Pro-Pro-Gly-OH in the presence of WSC-DMAP and subsequent deprotection with TFA gives 2b.
Double-caged fullerene acceptors: Effect of alkyl chain length on photovoltaic performance
Brotsman, Victor A.,Rybalchenko, Alexey V.,Zubov, Dmitry N.,Paraschuk, Dmitry Yu.,Goryunkov, Alexey A.
supporting information, p. 3278 - 3285 (2019/03/19)
We report the synthesis and spectroscopic and electrochemical characterization of the benzyl, C4, C6, C8, C9, C10, and C18n-alkyl esters of double-caged fullerene compounds (dFR). Counterintuitively, their solubility depends nonmonotonically on the alkyl chain length with a minimum at n-octyl. The series of dFR compounds were tested in organic solar cells (OSCs) as an acceptor material blended with the poly(3-hexylthiophene-2,5-diyl) (P3HT) donor. With the exception of the n-octadecyl derivative, the performance of the P3HT/dFR solar cells correlates with the solubility of the dFR component, likely due to the improved bulk heterojunction morphology and its favorable effect on JSCvia lower series resistance. A peak PCE of 3.0% was found for the n-nonyl compound, thus exceeding other known fullerene oligomers with fused fullerene cages or cross-linked fullerene dimers. The poor performance of compounds with too long alkyl chains like n-octadecyl reflects larger series resistance that results from a higher degree of phase segregation.
Preparation method of glycine benzyl ester toluene-4-sulfonate
-
Paragraph 0020; 0021, (2016/11/17)
The invention discloses a preparation method of glycine benzyl ester toluene-4-sulfonate. The preparation method comprises the steps of carrying out heating reflux after mixing p-toluene sulfonic acid monohydrate or p-toluene sulfonic acid tetrahydrate with methyl benzene, and separating generated water during reflux until no water is generated; then adding glycine and benzyl alcohol in a feed liquid, continuously carrying out heating reflux until no water is generated, separating the generated water, and continuously carrying out the reflux for 1.5 to 2.5 hours; then cooling, stirring and crystallizing, and filtering, washing and drying a crystal substance, thus obtaining a product. According to the preparation method disclosed by the invention, the water contained in p-toluene sulfonic acid is firstly separated, then the generated water can be continuously separated during continuous reaction processes by adding the glycine and the benzyl alcohol, and the reaction is enabled to proceed quickly, so that the reaction time is shortened, and the working efficiency is increased; meanwhile, the yield is increased, and the product quality is also increased.
