174543-78-3 Usage
General Description
1-N-Cbz-3-Methylpiperidine-3-carboxylic acid, also known as Cbz-L-3-Methylpiperidine-3-carboxylic acid, is a chemical compound that belongs to the class of carboxylic acids. It is used as an intermediate in the synthesis of pharmaceutical compounds and is commonly employed in the production of various drugs. The "1-N-Cbz" designation indicates the position of the Cbz (benzyloxycarbonyl) protecting group on the nitrogen atom of the piperidine ring. 1-N-Cbz-3-Methylpiperidine-3-carboxylic acid is commonly used in medicinal chemistry and drug development due to its potential biological activity and pharmacological properties. Additionally, it serves as a key building block in the creation of complex molecules for pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 174543-78-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,5,4 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 174543-78:
(8*1)+(7*7)+(6*4)+(5*5)+(4*4)+(3*3)+(2*7)+(1*8)=153
153 % 10 = 3
So 174543-78-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H19NO4/c1-15(13(17)18)8-5-9-16(11-15)14(19)20-10-12-6-3-2-4-7-12/h2-4,6-7H,5,8-11H2,1H3,(H,17,18)
174543-78-3Relevant articles and documents
PYRROLOPYRIDINES AS KINASE INHIBITORS
-
, (2009/12/23)
Compounds of Formula (I) are useful for inhibition of CHKl and/or CHK2. Methods of using compounds of Formula (I) and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.
On the Ritter reaction of cyclic hydroxyamines: Synthesis of conformationally-restricted reduced amide dipeptide isosteres
Taylor, G. Mark,Baker, Stewart J.,Gedney, Andrea,Pearson, David J.,Sibley, Graham E. M.
, p. 1297 - 1300 (2007/10/03)
The Ritter reactions of 3-alkyl-3-hydroxyazetidine or -piperidine derivatives give low yields of the desired products, whereas the 3-alkyl-3-hydroxy-pyrrolidine and 4-alkyl-4-hydroxy-piperidine derivatives react smoothly to give the corresponding acetamides. An alternative route to 3-acylamino-3-alkylpiperidines, which were designed as conformationally-restricted reduced amide dipeptide isosteres, was devised from nipecotic acid vai a Hofmann rearrangement.