175135-19-0Relevant articles and documents
Nucleophilic substitution of halogens with amines in 2- and 4-nitrophenols
Wrobel, Zbigniew,Kwast, Andrzej
, p. 259 - 262 (2007)
Fluorine and chlorine in halonitrophenols are efficiently replaced with alkylamines in acetonitrile or in an excess of the amine at elevated temperature. Georg Thieme Verlag Stuttgart.
ANTIBIOTIC COMPOUNDS
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Page/Page column 198; 199, (2018/03/25)
The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.
2-Aminobenzoxazole ligands of the hepatitis C virus internal ribosome entry site
Rynearson, Kevin D.,Charrette, Brian,Gabriel, Christopher,Moreno, Jesus,Boerneke, Mark A.,Dibrov, Sergey M.,Hermann, Thomas
supporting information, p. 3521 - 3525 (2014/07/22)
2-Aminobenzoxazoles have been synthesized as ligands for the hepatitis C virus (HCV) internal ribosome entry site (IRES) RNA. The compounds were designed to explore the less basic benzoxazole system as a replacement for the core scaffold in previously discovered benzimidazole viral translation inhibitors. Structure-activity relationships in the target binding of substituted benzoxazole ligands were investigated.