178451-61-1 Usage
Chemical compound
2',3'-dideoxyadenosine 5'-triphosphate (ddATP) is a chemical compound that is commonly used in biochemical research.
Use in DNA sequencing
It is used as a chain-terminating nucleotide for DNA sequencing.
Structure modification
It is a modified form of adenosine 5'-triphosphate (ATP) in which the 2' and 3' hydroxyl groups on the ribose sugar are replaced by hydrogen atoms.
Inability to form phosphodiester bond
This modification renders ddATP unable to form the next phosphodiester bond in the DNA strand during replication.
Determining DNA sequence
This property makes ddATP useful for determining the sequence of a DNA molecule.
Antiviral drug development
2',3'-dideoxyadenosine 5'-triphosphate (ddATP) is also utilized in the development of antiviral drugs for the treatment of HIV/AIDS.
Inhibition of viral enzyme
It can inhibit the activity of the viral reverse transcriptase enzyme.
Check Digit Verification of cas no
The CAS Registry Mumber 178451-61-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,4,5 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 178451-61:
(8*1)+(7*7)+(6*8)+(5*4)+(4*5)+(3*1)+(2*6)+(1*1)=161
161 % 10 = 1
So 178451-61-1 is a valid CAS Registry Number.
