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179324-21-1

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179324-21-1 Usage

General Description

Z-Leu-Leu-BoroLeu-Pinanediol (MG261) is a synthetic chemical compound that possesses boronic acid functionality. It is a potent and selective inhibitor of the proteasome, a key cellular protein degradation machinery responsible for regulating various cellular processes. MG261 has been widely used as a research tool in the study of proteasome function and its role in disease. The boronic acid moiety in MG261 allows it to specifically target and bind to the catalytic site of the proteasome, effectively blocking its activity and leading to the accumulation of ubiquitinated proteins, ultimately resulting in cell death. As a result, MG261 has shown potential as a therapeutic agent for the treatment of cancer and other diseases characterized by dysregulated proteasome activity.

Check Digit Verification of cas no

The CAS Registry Mumber 179324-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,3,2 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 179324-21:
(8*1)+(7*7)+(6*9)+(5*3)+(4*2)+(3*4)+(2*2)+(1*1)=151
151 % 10 = 1
So 179324-21-1 is a valid CAS Registry Number.

179324-21-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(Benzyloxy)carbonyl]-L-leucyl-N-{(1R)-3-methyl-1-[(1S,2R,6S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]dec-4-yl]butyl}-D-leucinamide

1.2 Other means of identification

Product number -
Other names N-[(Phenylmethoxy)Carbonyl]-L-Leucyl-N-[1-[(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-Trimethyl-4,6-Methano-1,3,2-Benzodioxaborol-2-Yl]-3-Methylbutyl]-L-Leucinamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:179324-21-1 SDS

179324-21-1Upstream product

179324-21-1Downstream Products

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