18034-37-2

• 

• Basic information

  1. Product Name: 2-(3,4-dimethoxyphenyl)-N-[(E)-(3,4-dimethoxyphenyl)methylidene]ethanamine
  2. Synonyms:
  3. CAS NO:18034-37-2
  4. Molecular Formula: C₁₉H₂₃NO₄
  5. Molecular Weight: 329.3902
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 18034-37-2.mol
  9. Article Data: 7

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 459.2°C at 760 mmHg
  3. Flash Point: 185.9°C
  4. Appearance: N/A
  5. Density: 1.06g/cm³
  6. Vapor Pressure: 3.53E-08mmHg at 25°C
  7. Refractive Index: 1.513
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: 2-(3,4-dimethoxyphenyl)-N-[(E)-(3,4-dimethoxyphenyl)methylidene]ethanamine(CAS DataBase Reference)
  11. NIST Chemistry Reference: 2-(3,4-dimethoxyphenyl)-N-[(E)-(3,4-dimethoxyphenyl)methylidene]ethanamine(18034-37-2)
  12. EPA Substance Registry System: 2-(3,4-dimethoxyphenyl)-N-[(E)-(3,4-dimethoxyphenyl)methylidene]ethanamine(18034-37-2)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 18034-37-2(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

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• Benzeneethanamine,N-[(3,4-dimethoxyphenyl)methylene]-3,4-dimethoxy-

  Cas No: 18034-37-2

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
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• Benzeneethanamine,N-[(3,4-dimethoxyphenyl)methylene]-3,4-dimethoxy- cas 18034-37-2

  Cas No: 18034-37-2

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• Hangzhou Fandachem Co.,Ltd
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• Benzeneethanamine,N-[(3,4-dimethoxyphenyl)methylene]-3,4-dimethoxy-

  Cas No: 18034-37-2

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• yuyongmei
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18034-37-2 Usage

Type of compound

alkaloid

Origin

naturally occurring in several plant species

Psychoactive properties

exhibits sedative and analgesic effects

Traditional uses

used in traditional Chinese medicine for its therapeutic effects

Potential medical applications

bronchodilator, anti-inflammatory agent, cancer treatment (cytotoxic effects on various cancer cell lines)

Current status

under investigation, more research needed to understand its mechanism of action and potential medical uses.

Check Digit Verification of cas no

The CAS Registry Mumber 18034-37-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,0,3 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18034-37:
(7*1)+(6*8)+(5*0)+(4*3)+(3*4)+(2*3)+(1*7)=92
92 % 10 = 2
So 18034-37-2 is a valid CAS Registry Number.

18034-37-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-(3,4-dimethoxyphenyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]methanimine

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18034-37-2 SDS

18034-37-2Upstream product

• 63987-72-4 2,2-dibromo-1-(3,4-dimethoxyphenyl)ethan-1-one 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

18034-37-2Downstream Products

• 24997-85-1 N-<2-(3,4-dimethoxybenzyl)(3,4-dimethoxyphenyl)>ethanamine 
• 96839-24-6 N-(3,4-dimethoxybenzyl)-N'-methyl-2-(3,4-dimethoxyphenyl)ethanamine 
• 144344-81-0 N-(3,4-dimethoxybenzyl)-N'-formyl-2-(3,4-dimethoxyphenyl)ethanamine 
• 94027-34-6 4,4'-(2-aza-butanediyl)-di-pyrocatechol 
• 15547-55-4 1-(3',4'-dimethoxyphenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 

18034-37-2Relevant articles and documents

Synthesis of 1-aryltetrahydroisoquinoline alkaloids and their analogs

Zhurakulov,Vinogradova,Levkovich

, p. 70 - 74 (2013/06/27)

Three alkaloids of the cryptostylin series and 20 monomolecular and 3 bimolecular 1-aryltetrahydroisoquinoline derivatives were prepared using the Picte-Spengler reaction.

Synthesis and biological evaluation of berberine analogues as novel up-regulators for both low-density-lipoprotein receptor and insulin receptor

Wang, Yan-Xiang,Wang, Yu-Ping,Zhang, Hao,Kong, Wei-Jia,Li, Ying-Hong,Liu, Fei,Gao, Rong-Mei,Liu, Ting,Jiang, Jian-Dong,Song, Dan-Qing

scheme or table, p. 6004 - 6008 (2010/06/16)

Berberine (BBR) is a natural compound with up-regulating activity on both low-density-lipoprotein receptor (LDLR) and insulin receptor (InsR). This one-drug-multiple-target characteristic might be suitable for the treatment of metabolic syndrome. In searching for up-regulators effective for both LDLR and InsR expression, the structure-activity relationship (SAR) analysis for BBR analogues was done. Fourteen BBR analogues were designed, synthesized and biologically evaluated. SAR analysis revealed that appropriate modifications on the phenyl ring A or D of BBR might retain the up-regulatory activities on the expression of both LDLR and InsR. Among these compounds, compound 13a bearing 9-methoxy and 10-hydroxyl on the ring D showed promising activities on either LDLR or InsR gene expression. The 10-hydroxyl of 13a could be an arm to connect proper chemical groups for optimizing drug-bioavailability in vivo. Thus, 13a could be considered to be a parent compound to make pro-drugs for either blood lipids or glucose.

Berberis ALKALOIDS. XXII. INTEBRININE AND INTEBRIMINE - NEW ALKALOIDS FROM Berberis integerrima

Karimov, A.,Vinogradova, V. I.,Shakirov, R.

, p. 57 - 60 (2007/10/02)

The known alkaloids reticuline, isoboldine, isocorydine, glaucine, armepavine, oxyacanthine, and heliamine and the new alkaloids intebrinine and intebrimine have been isolated from the total alkaloids of the leaves of Berberis integerrima, and structures

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