183609-98-5Relevant articles and documents
Synthesis of natural and modified trapoxins, useful reagents for exploring histone deacetylase function
Taunton, Jack,Collins, Jon L.,Schreiber, Stuart L.
, p. 10412 - 10422 (1996)
Trapoxin, a cyclotetrapeptide isolated from the fungus Helicoma ambiens, profoundly affects mammalian cell growth and morphology. In this paper, we describe syntheses of trapoxin, [3H]trapoxin, and K-trap, a trapoxin-based affinity reagent. The