185525-42-2

• 

• Basic information

  1. Product Name: TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE
  2. Synonyms: TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE;tert-Butyl 3-hydroxyspiro[indan-1,4'-piperidine]-1'-carboxylate
  3. CAS NO:185525-42-2
  4. Molecular Formula: C18H25NO3
  5. Molecular Weight: 303.4
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 185525-42-2.mol
  9. Article Data: 7

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE(CAS DataBase Reference)
  10. NIST Chemistry Reference: TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE(185525-42-2)
  11. EPA Substance Registry System: TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE(185525-42-2)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 185525-42-2(Hazardous Substances Data)

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• Usage
• SDS
• Upstream product
• Downstream Products
• Article

185525-42-2 Suppliers

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• tert-Butyl 3-hydroxyspiro[indan-1,4'-piperidine]-1'-carboxylate

  Cas No: 185525-42-2

• USD $ 3.0-3.0 / Kilogram

• 1 Kilogram

• 1-100 Metric Ton/Month

• Dayang Chem (Hangzhou) Co.,Ltd.
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• tert-Butyl 3-hydroxyspiro[indan-1,4'-piperidine]-1'-carboxylate

  Cas No: 185525-42-2

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• 10 Gram

• 500 Kilogram/Month

• Zibo Hangyu Biotechnology Development Co., Ltd
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• tert-Butyl 3-hydroxyspiro[indan-1,4'-piperidine]-1'-carboxylate

  Cas No: 185525-42-2

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• GIHI CHEMICALS CO.,LIMITED
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• tert-Butyl 3-hydroxyspiro[indan-1,4'-piperidine]-1'-carboxylate

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• tert-Butyl 3-hydroxyspiro[indan-1,4'-piperidine]-1'-carboxylate cas 185525-42-2

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• Hangzhou Fandachem Co.,Ltd
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• TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE

  Cas No: 185525-42-2

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• ZHEJIANG JIUZHOU CHEM CO.,LTD
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• tert-butyl 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate

  Cas No: 185525-42-2

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• 1 Gram

• 1000 Gram/Week

• suzhou BetterBioChem Co., Ltd.
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• TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE

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• U-Chemo Holding Co.,Limited
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• TERT-BUTYL 3-OXOSPIRO[INDAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE

  Cas No: 185525-42-2

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• Wuxi Morality Chemical Co., Ltd
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• Tert-butyl 2,3-dihydro-1h-spiro[isoquinoline-4,4’-piperidine]-1’-carboxylate

  Cas No: 185525-42-2

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• Shanghai Dano Pharmaceutical Co.,Ld.
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185525-42-2 Usage

Uses

tert-Butyl3-oxospiro[indan-1,4''-piperidine]-1''-carboxylate is a useful intermediate in the preparation of spiroindane growth hormone secretagogues.

Check Digit Verification of cas no

The CAS Registry Mumber 185525-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,5,2 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 185525-42:
(8*1)+(7*8)+(6*5)+(5*5)+(4*2)+(3*5)+(2*4)+(1*2)=152
152 % 10 = 2
So 185525-42-2 is a valid CAS Registry Number.

185525-42-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	tert-butyl 1-hydroxyspiro[1,2-dihydroindene-3,4'-piperidine]-1'-carboxylate

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:185525-42-2 SDS

185525-42-2Upstream product

• 118753-70-1 N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine 
• 95-13-6 1-indene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 137419-24-0 1'-(tert-butyloxycarbonyl)spiro<1H-indene-1,4'-piperidine> 
• 13292-87-0 dimethylsulfide borane complex 

185525-42-2Downstream Products

• 159634-59-0 2,3-dihydro-3-oxo-spiro[1H-indene-1,4'-piperidine]-1'-carboxylic acid 1,1-dimethylethyl ester 

185525-42-2Relevant articles and documents

NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

-

Paragraph 0256; 0258, (2019/05/16)

Provided are 2-(piperidin-1-yl)pyrimidin-4(3H)-ones or pharmaceutically acceptable salts thereof, each characterized by having a 1,8-diazaspiro[4.5]deca-3-ene, 1-oxa-8-azaspiro[4.5]deca-3-ene, 2,8-diazaspiro[4.5]deca-3-ene, 2-oxa-8-azaspiro[4.5]deca-3-ene, 2,9-diazaspiro[5.5]undeca-3-ene, 1-oxa-9-azaspiro[5.5]undeca-3-ene, 1,9-diazaspiro[5.5]undeca-4-ene, or 3,9-diazaspiro[5.5]undeca-1-ene structure represented by the following general formula (1):

NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS

-

, (2018/10/19)

This invention relates to certain novel pyrazine derivatives (Formula I) as SHP2 inhibitors which is shown as formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention is directed to fused heterocyclic group derivatives useful as inhibitors of SHP2, methods for producing such compounds and methods for treating a SHP2-mediated disorder.

SPIRO-PIPERIDINE DERIVATIVES

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Page/Page column 28; 29, (2008/12/06)

Present invention is concerned with novel indol- 2-yl-carbonyl-spiro-piperidine derivatives as Vla receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention andlor treatment of anxiety and depressive disorders and other diseases. The compounds of present invention have the general Formula (I) wherein R1 to R 11 and X are as defined in the description

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