18732-58-6Relevant articles and documents
Rapid and efficient protocol for Willgerodt–Kindler’s thioacetamides catalyzed by sulfated polyborate
Rekunge, Deelip S.,Khatri, Chetan K.,Chaturbhuj, Ganesh U.
, p. 2091 - 2095 (2017/10/06)
Abstract: A simple and efficient method for the synthesis of one-pot, three-component thioacetamides via Willgerodt–Kindler reaction was developed using a sulfated polyborate catalyst. The method described the reaction of ketones, sulfur, and secondary am
Three-component reaction between alkynes, elemental sulfur, and aliphatic amines: A general, straightforward, and atom economical approach to thioamides
Nguyen, Thanh Binh,Tran, Minh Quan,Ermolenko, Ludmila,Al-Mourabit, Ali
supporting information, p. 310 - 313 (2014/01/23)
A general, straightforward, and atom-economical three-component synthesis of thioamides from alkynes, elemental sulfur, and aliphatic amines has been developed.
Thionation of amides using a solid-supported P2S5 reagent under microwave irradiation
Lagiakos, Helen Rachel,Walker, Ashley,Aguilar, Marie-Isabel,Perlmutter, Patrick
experimental part, p. 5131 - 5132 (2011/10/12)
In this Letter, we describe an improved method for the thionation of amides. Using a solid-supported P2S5 reagent, heating under microwave irradiation furnished thioamides in good to excellent yields, with a significantly reduced reaction time compared with that achieved under conventional heating. Furthermore, a change of solvent from that described in the literature enabled a simplified work-up and purification of the products.