189268-37-9 Usage
Chemical structure
1H-Pyrrole-2-carbonitrile, 1-[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]
Pyrrole derivative
A chemical compound based on the pyrrole ring system, which consists of a five-membered ring with one nitrogen atom and four carbon atoms.
Carbonitrile group
A functional group with a triple bond between carbon and nitrogen (C≡N) attached to the 2-position of the pyrrole ring.
Phenyl ring
A six-membered carbon ring with alternating single and double bonds, substituted with various functional groups.
Two chlorine atoms
Attached to the 2 and 4 positions of the phenyl ring.
Quinolinyl group
A nitrogen-containing aromatic ring system attached to the 3-position of the phenyl ring.
Biological activity potential
The presence of the quinolinyl group and carbonitrile group suggests that this compound may have biological activity, as such derivatives have been used in antimalarial and antitumor agents.
Wide range of pharmacological properties
Nitrile-containing compounds are known to exhibit various pharmacological properties, which may make this compound a promising candidate for further study.
Drug discovery and development
The specific combination of functional groups in this compound may make it a potential candidate for drug discovery and development efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 189268-37-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,2,6 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 189268-37:
(8*1)+(7*8)+(6*9)+(5*2)+(4*6)+(3*8)+(2*3)+(1*7)=189
189 % 10 = 9
So 189268-37-9 is a valid CAS Registry Number.
189268-37-9Relevant articles and documents
Heterocyclic compounds as bradykinin antagonists
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Page column 27, (2010/02/04)
This invention relates to a compound of the formula: wherein A1is lower alkylene, R1is substituted quinolyl, etc., R2is hydrogen, halogen or lower alkyl, R3is halogen or lower alkyl, and R4is a group
A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 4. Discovery of novel frameworks mimicking the active conformation
Abe, Yoshito,Kayakiri, Hiroshi,Satoh, Shigeki,Inoue, Takayuki,Sawada, Yuki,Inamura, Noriaki,Asano, Masayuki,Aramori, Ichiro,Hatori, Chie,Sawai, Hiroe,Oku, Teruo,Tanaka, Hirokazu
, p. 4587 - 4598 (2007/10/03)
In recent articles we reported the identification of a series of 8- [[2,6-dichloro-3-[N-methyl-N-[(E)- (substituted)acryloylglycyl]amino]benzyl]oxy]-2-methylimidazo[1,2- a]pyridines as the first orally active non-peptide bradykinin (BK) B2 rece
