191671-46-2 Usage
Description
BIOTINAMIDOHEXANOIC ACID 3-SULFO-N-HYDROXYSUCCINIMIDE ESTER SODIUM SALT, also known as Sulfo-NHS-LC-Biotin, is a linker containing a sulfo-NHS group and a biotin moiety. It is a white solid that enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates for conjugation with primary amines. The biotinylation can react with amine molecules in the presence of activator EDC or HATU.
Uses
Used in Biochemical Research:
BIOTINAMIDOHEXANOIC ACID 3-SULFO-N-HYDROXYSUCCINIMIDE ESTER SODIUM SALT is used as a biotinylation reagent for attaching biotin molecules to antibodies and carriers in Protein Avidin-Biotin systems on solid surfaces, such as plastics. This application helps reduce antigenicity and enhances the detection of DNA on nitrocellulose.
Used in Diagnostics and Detection:
In the Diagnostics and Detection industry, BIOTINAMIDOHEXANOIC ACID 3-SULFO-N-HYDROXYSUCCINIMIDE ESTER SODIUM SALT is used as a detection enhancer for improving the detection of DNA on nitrocellulose membranes. The increased sensitivity and specificity provided by this biotinylation reagent are crucial for accurate and reliable results in various diagnostic assays.
Used in Drug Delivery Systems:
BIOTINAMIDOHEXANOIC ACID 3-SULFO-N-HYDROXYSUCCINIMIDE ESTER SODIUM SALT can be used in the development of drug delivery systems, particularly for targeting specific molecules or cells. The biotinylation process allows for the attachment of drugs or other therapeutic agents to antibodies or carriers, enabling more precise and efficient delivery to the desired target.
Spacer Arm:
The spacer arm of BIOTINAMIDOHEXANOIC ACID 3-SULFO-N-HYDROXYSUCCINIMIDE ESTER SODIUM SALT is 22.4 Angstroms, which provides an optimal distance between the biotin molecule and the target molecule, ensuring efficient binding and interaction.
Check Digit Verification of cas no
The CAS Registry Mumber 191671-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,6,7 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 191671-46:
(8*1)+(7*9)+(6*1)+(5*6)+(4*7)+(3*1)+(2*4)+(1*6)=152
152 % 10 = 2
So 191671-46-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H30N4O9S2.Na/c25-15(7-4-3-6-13-18-12(11-34-13)22-20(29)23-18)21-9-5-1-2-8-17(27)33-24-16(26)10-14(19(24)28)35(30,31)32;/h12-14,18H,1-11H2,(H,21,25)(H2,22,23,29)(H,30,31,32);/q;+1/p-1/rC20H29N4NaO9S2/c25-34-36(31,32)14-10-16(27)24(19(14)29)33-17(28)8-2-1-5-9-21-15(26)7-4-3-6-13-18-12(11-35-13)22-20(30)23-18/h12-14,18H,1-11H2,(H,21,26)(H2,22,23,30)
