1919045-01-4
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Basic information
- Product Name: Azido-PEG4- Boc-Hydrazide
- Synonyms: Azido-PEG4- Boc-Hydrazide;Azido-PEG4-t-Boc-Hydrazide
- CAS NO:1919045-01-4
- Molecular Formula: C16H31N5O7
- Molecular Weight: 405.44664
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1919045-01-4.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Azido-PEG4- Boc-Hydrazide(CAS DataBase Reference)
- NIST Chemistry Reference: Azido-PEG4- Boc-Hydrazide(1919045-01-4)
- EPA Substance Registry System: Azido-PEG4- Boc-Hydrazide(1919045-01-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1919045-01-4(Hazardous Substances Data)
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1919045-01-4 Usage
Description
Azido-PEG4-t-Boc-Hydrazide is a Boc-protected PEG linker that features an azide group (N3) and a hydrophilic PEG spacer, which enhances solubility in aqueous media. The azide group is capable of reacting with alkyne, BCN, and DBCO through Click Chemistry, resulting in a stable triazole linkage. Additionally, the Boc site can be deprotected under mild acidic conditions, leading to the formation of a reactive hydrazide that can be coupled with various carbonyl groups.Uses
Used in Bioconjugation:Azido-PEG4-t-Boc-Hydrazide is used as a bioconjugation agent for the formation of stable covalent bonds between biomolecules and other chemical entities. The application reason is its ability to form a stable triazole linkage through Click Chemistry, which is useful in the creation of bioconjugates for various research and therapeutic purposes.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Azido-PEG4-t-Boc-Hydrazide is used as a component in the development of drug delivery systems. The application reason is its hydrophilic PEG spacer, which increases solubility and bioavailability of the drug, as well as its reactive hydrazide group that allows for the coupling of drugs with carbonyl groups, enhancing the overall effectiveness of the drug delivery system.
Used in Chemical Synthesis:
Azido-PEG4-t-Boc-Hydrazide is used as an intermediate in chemical synthesis, particularly in the synthesis of complex molecules and macromolecules. The application reason is its versatility in forming stable triazole linkages and its ability to be deprotected and coupled with various carbonyl groups, making it a valuable building block in the synthesis of a wide range of chemical compounds.
Used in Materials Science:
In the field of materials science, Azido-PEG4-t-Boc-Hydrazide is used as a component in the development of novel materials with specific properties. The application reason is its ability to form stable covalent bonds and its hydrophilic PEG spacer, which can contribute to the overall properties of the material, such as solubility, biocompatibility, and stability.
Check Digit Verification of cas no
The CAS Registry Mumber 1919045-01-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,9,1,9,0,4 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.Calculate Digit Verification of CAS Registry Number 1919045-01:
(9*1)+(8*9)+(7*1)+(6*9)+(5*0)+(4*4)+(3*5)+(2*0)+(1*1)=174
174 % 10 = 4
So 1919045-01-4 is a valid CAS Registry Number.
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1919045-01-4Downstream Products
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Azido-PEG4- Boc-Hydrazide
