193079-69-5

• 

• Basic information

  1. Product Name: Tabimorelin
  2. Synonyms: Tabimorelin;Tabimorelin [inn];Unii-L51cbe03kf;N-[(2E)-5-Amino-5-methyl-1-oxo-2-hexenyl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamidehemifumarate
  3. CAS NO:193079-69-5
  4. Molecular Formula: C₃₂H₄₀N₄O₃
  5. Molecular Weight: 1173.46
  6. EINECS: N/A
  7. Product Categories: Amines;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
  8. Mol File: 193079-69-5.mol
  9. Article Data: 2

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 794.4°Cat760mmHg
  3. Flash Point: 434.2°C
  4. Appearance: /
  5. Density: 1.146g/cm³
  6. Vapor Pressure: 0mmHg at 25°C
  7. Refractive Index: 1.6
  8. Storage Temp.: Desiccate at RT
  9. Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
  10. Stability: Light Sensitive
  11. CAS DataBase Reference: Tabimorelin(CAS DataBase Reference)
  12. NIST Chemistry Reference: Tabimorelin(193079-69-5)
  13. EPA Substance Registry System: Tabimorelin(193079-69-5)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 193079-69-5(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

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• TabiMorelin

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• Henan Tianfu Chemical Co., Ltd.
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• Tabimorelin

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• HENAN SUNLAKE ENTERPRISE CORPORATION
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• Tabimorelin CAS NO.193079-69-5

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• Tabimorelin

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• Tabimorelin

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• Finetech Industry Limited
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• TabiMorelin heMifuMarate;N-[(2E)-5-AMino-5-Methyl-1-oxo-2-hexenyl]-N-Methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-diMethyl-D-phenylalaninaMideheMifuMarate

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• Wuxi Morality Chemical Co., Ltd
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• Tabimorelin

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• Topbatt Chemical Co., Ltd.
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• Tabimorelin

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• Shenzhen Sumshine Biotech Co., Ltd.
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193079-69-5 Usage

Uses

NN703 (Tabimorelin) is an orally active growth hormone (GH) secretagogue intended for use as an alternative to daily injections of GH. In vitro studies in human liver microsomes have indicated that NN703 is a mechanism-based inhibitor of CYP3A4.

Biological Activity

Potent, orally active ghrelin receptor (GHS-R1a) agonist (K i = 50 nM at human recombinant GHS-R1a). Stimulates GH release from rat pituitary cells with an EC 50 value of 2.7 nM. Induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats.

Check Digit Verification of cas no

The CAS Registry Mumber 193079-69-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,0,7 and 9 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 193079-69:
(8*1)+(7*9)+(6*3)+(5*0)+(4*7)+(3*9)+(2*6)+(1*9)=165
165 % 10 = 5
So 193079-69-5 is a valid CAS Registry Number.

InChI:InChI=1/C32H40N4O3/c1-32(2,33)19-11-16-29(37)35(4)28(22-24-17-18-25-14-9-10-15-26(25)20-24)31(39)36(5)27(30(38)34-3)21-23-12-7-6-8-13-23/h6-18,20,27-28H,19,21-22,33H2,1-5H3,(H,34,38)/b16-11+/t27-,28-/m1/s1

193079-69-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	Tabimorelin

1.2 Other means of identification

Product number	-
Other names	(E)-5-amino-N,5-dimethyl-N-[(2R)-1-[methyl-[(2R)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]hex-2-enamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:193079-69-5 SDS

193079-69-5Upstream product

• 193085-20-0 ((3E)-1,1-Dimethyl-4-(N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)carbamoyl)but-3-enyl)carbamic acid tert-butyl ester 
• 147577-61-5 (2R)-2-(N-(tert-butoxycarbonyl)-N-methylamino)-3-(2-naphthyl)-propionic acid 
• 193085-19-7 N-Methyl-N-{(1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl}carbamic acid tert-butyl ester 
• 186840-95-9 (2R)-N-Methyl-2-methylamino-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)-3-(2-naphthyl)propionamide 
• 193085-18-6 N-Methyl-N-((R)-1-(methylcarbamoyl)-2-phenylethyl)carbamic acid tert-butyl ester 
• 193150-11-7 (R)-N-Methyl-2-methylamino-3-phenylpropionamide 
• 167216-22-0 tert-butyl (3-hydroxy-1,1-dimethyl-propyl)-carbamate 
• 181646-38-8 (1,1-dimethyl-3-oxo-propyl)-carbamic acid tert-butyl ester 
• 129765-95-3 3-[(tert-butoxycarbonyl)amino]-3-methylbutanoic acid 
• 37553-65-4 N-tert-butoxycarbonyl-N-methyl-D-phenylalanine 
• 181646-40-2 ethyl (2E)-5-(tert-butoxycarbonylamino)-5-methylhex-2-enoate 
• 181646-42-4 (2E)-5-(tert-butyloxycarbonylamino)-5-methylhex-2-enoic acid 

193079-69-5Downstream Products

193079-69-5Relevant articles and documents

Use of growth hormone or a growth hormone secretagogue for promoting bone formation

-

, (2008/06/13)

The invention provides a method of enhancing the healing of bone fractures in an animal subjected to distraction osteogenesis, the method comprising administering, to the animal in need thereof, a growth hormone or a growth hormone secretagogue in an amou

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