19432-68-9Relevant articles and documents
One-dimensional optoelectronic nanostructures derived from the aqueous self-assembly of π-conjugated oligopeptides
Diegelmann, Stephen R.,Gorham, Justin M.,Tovar, John D.
, p. 13840 - 13841 (2008)
The aqueous self-assembly of oligopeptide-flanked π-conjugated molecules into discrete one-dimensional nanostructures is described. Unique to these molecules is the fact that the π-conjugated unit has been directly embedded within the peptide backbone by way of a synthetic amino acid with π-functionality that is compatible with standard Fmoc-based peptide synthesis. The peptide-based molecular design enforces intimate π-π communication within the aggregate after charge-screening and self-assembly, making these nanostructures attractive for optical or electronic applications in biological environments. The synthesis and assembly are reported along with spectroscopic and morphological characterization of the new nanomaterials. Copyright
THIENYL-2-ACETIC ACID AS A SYNTHETIC AGENT FOR THE PREPARATION OF MACROCYCLIC COMPOUNDS CONTAINING A THIOPHENE RING
Taits, S. Z.,Bulgakova, V. N.
, p. 195 - 201 (1984)
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B(C6F5)3-catalyzed O-H insertion reactions of diazoalkanes with phosphinic acids
Jiang, Jun,Zhang, Xinzhi,Zhang, Yangyang,Zhao, Jincheng
supporting information, p. 5772 - 5776 (2021/07/12)
A highly efficient base-, metal-, and oxidant-free catalytic O-H insertion reaction of diazoalkanes and phosphinic acids in the presence of B(C6F5)3has been developed. This powerful methodology provides a green approach towards the synthesis of a broad spectrum of α-phosphoryloxy carbonyl compounds with good to excellent yields (up to 99% yield). The protocol features the advantages of operational simplicity, high atom economy, practicality, easy scalability and environmental friendliness.
Thiophene-based water-soluble fullerene derivatives as highly potent antiherpetic pharmaceuticals
Fedorova, Natalia E.,Godovikov, Ivan A.,Klimova, Regina R.,Kraevaya, Olga A.,Kushch, Alla A.,Mishchenko, Denis V.,Peregudov, Alexander S.,Schols, Dominique,Shestakov, Alexander F.,Troshin, Pavel A.
supporting information, p. 8702 - 8708 (2020/11/17)
Here we report the Friedel-Crafts arylation of chlorofullerenes C60Cl6 and C70Cl8 with thiophene-based methyl esters. While C60Cl6 formed expected Cs-C60R5Cl products, C70Cl8 demonstrated a tendency for both substitution of chlorine atoms and addition of an extra thiophene unit, thus forming Cs-C70R8 and C1-C70R9H compounds. The synthesized water-soluble C60 and C70 fullerene derivatives with thiophene-based addends demonstrated high activity against a broad range of viruses, including human immunodeficiency virus, influenza virus, cytomegalovirus, and herpes simplex virus. The record activity of C70 fullerene derivatives against herpes simplex virus together with low toxicity in mice makes them promising candidates for the development of novel non-nucleoside antiherpetic drugs.
