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19432-88-3

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19432-88-3 Usage

Uses

2-Pyrrolidin-2-yl-ethanol can be used as inhibitor of c-Kit kinase to treat cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 19432-88-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,3 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19432-88:
(7*1)+(6*9)+(5*4)+(4*3)+(3*2)+(2*8)+(1*8)=123
123 % 10 = 3
So 19432-88-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H13NO/c8-5-3-6-2-1-4-7-6/h6-8H,1-5H2

19432-88-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-pyrrolidin-2-ylethanol

1.2 Other means of identification

Product number -
Other names 2-pyrrolidineethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19432-88-3 SDS

19432-88-3Relevant articles and documents

Participation of a Neighboring Amide Group in the Hydrolytic C-OAr Cleavage of 1-Acyl-2-(2-phenoxyethyl)pyrrolidines

Dobrzeniecka, Regina

, p. 901 - 910 (2007/10/02)

Measurements are reported on the kinetics of acid-catalyzed hydrolysis of 1-acetyl- and 1-propionyl-2-(2-phenoxyethyl)pyrrolidine.The pseudo-first-order rate constants, kobs, were obtained: kobs = kA + kB, where kA and kB refer to the rate constants for the formation of 2-(2-phenoxyethyl)pyrrolidine A and 2-(2-hydroxyethyl)pyrrolidine B, respectively.Formation of the product B with consequent liberation of the phenol is attributed to the effect of neighboring amide group participation.A mechanism comprising a six-membered cyclic intermediate has been proposed for hydrolysis leading to cleavage of the ether bond.

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