195136-68-6Relevant articles and documents
Multi-faceted reactivity of N-fluorobenzenesulfonimide (NFSI) under mechanochemical conditions: fluorination, fluorodemethylation, sulfonylation, and amidation reactions
Ardila-Fierro, Karen J.,Bari?i?, Dajana,Geneste, Hervé,Hernández, José G.
supporting information, p. 182 - 189 (2022/03/01)
In the search for versatile reagents compatible with mechanochemical techniques, in this work we studied the reactivity of N-fluorobenzenesulfonimide (NFSI) by ball milling. We corroborated that, by mechanochemistry, NFSI can engage in a variety of reactions such as fluorinations, fluorodemethylations, sulfonylations, and amidations. In comparison to the protocols reported in solution, the mechanochemical reactions were accomplished in the absence of solvents, in short reaction times, and in yields comparable to or higher than their solvent-based counterparts.
AROMATIC-SUBSTITUTED XANTHENE DYE
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Paragraph 0194, (2016/12/22)
PROBLEM TO BE SOLVED: To provide a useful compound used for independent detection of multiple spatially overlapping analytes in a mixture, for example, single-tube multiplex DNA probe assays, immunoassays, multicolor DNA sequencing methods and the like. SOLUTION: There is provided an aromatic-substituted xanthene dye represented by the following formula. (Y1 and Y2 each independently represents hydroxyl, oxygen, iminium, a linking group or an amine; Y1 forms a cyclic amine together with R2 or Y2 forms a cyclic amine together with R3; R2, R3, R5 and R7 each independently represents H, F, Cl, a lower alkyl, a lower alkene, sulfonate, sulfone, iminium, amide, nitrile, a lower alkoxy, phenyl or a linking group; R1 represents a single ring or a polycyclic aromatic or the like; R4 represents H, F, alkyl, amino or the like; and R6 represents acetylene, a lower alkyl or the like.) COPYRIGHT: (C)2015,JPO&INPIT
Transformations of organic molecules with F-TEDA-BF4 in ionic liquid media
Pavlinac, Jasminka,Zupan, Marko,Stavber, Stojan
experimental part, p. 2394 - 2409 (2009/12/03)
The transformations of organic molecules with F-TEDA-BF4 (1) were investigated in the hydrophilic ionic liquid (IL) 1-butyl-3-methyl- imidazolium tetrafluoroborate ([bmim][BF4], 2) and the hydrophobic IL 1-butyl-3-methyl-imidazolium hexafluorophosphate ([bmim][PF6], 3). The range of substrates included alkyl substituted phenols 4a-c, 9, 13, 1,1-diphenylethene (15), alkyl aryl ketones 19-22, aldehydes 23-25 and methoxy-substituted benzene derivatives 26-30. The evaluation of the outcome of reactions performed in IL media in comparison to those of the corresponding reactions in conventional organic solvents revealed that the transformations in IL are less efficient and selective. The effect of the presence of a nucleophile (MeOH, H2O, MeCN) on the course of reaction was also studied.
