195137-72-5Relevant articles and documents
4-(trans-4-methylcyclohexyl)-4-oxobutyric acid (JTT-608). A new class of antidiabetic agent
Shinkai, Hisashi,Ozeki, Hidekazu,Motomura, Takahisa,Ohta, Takeshi,Furukawa, Noboru,Uchida, Itsuo
, p. 5420 - 5428 (2007/10/03)
During an investigation of drugs for improving the β-cell response to glucose, we found that 4-cyclohexyl-4-oxobutyric acid selectively improved glucose-stimulated insulin release and glucose tolerance in both normal and diabetic rats. A series of 4-cyclo