19556-54-8 Usage
General Description
1-(5-chloro-5-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione is a chemical compound that is a pyrimidine analogue. It is composed of a pyrimidine ring with a pentofuranosyl group attached to it, as well as a chlorine atom at the 5th position. 1-(5-chloro-5-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione is a nucleoside analog that can be found in various antiviral and anticancer drugs due to its ability to interfere with DNA and RNA synthesis. It exhibits potent antiviral and antitumor activities and is commonly used as a chemical building block in the synthesis of pharmaceuticals. Its chemical structure and properties make it a valuable tool in the development of new drugs and therapies for a variety of diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 19556-54-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,5,5 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19556-54:
(7*1)+(6*9)+(5*5)+(4*5)+(3*6)+(2*5)+(1*4)=138
138 % 10 = 8
So 19556-54-8 is a valid CAS Registry Number.
19556-54-8Relevant articles and documents
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Dods,Roth
, p. 165 (1969)
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Chlorination of nucleosides by N-chlorodiisopropylamine and triphenylphosphine
Zhou, Yi-Sui,Miao,Zhao, Yu-Fen
, p. 671 - 673 (2007/10/03)
The combination of N-chlorodiisopropylamine and triphenylphosphine (1) was exploited as a new method for chlorination of the hydroxyl group on the nucleosides. A possible mechanism involving an oxyphosphonium intermediate 2a and a phosphorane intermediate 2b was proposed based on the results from 31P NMR spectrum.
9-(4-METHOXYPHENYL)XANTHEN-9-THIOL: A USEFUL REAGENT FOR THE PREPARATION OF THIOLS
Marriott, Jonathan H.,Mottahedeh, Mina,Reese, Colin B.
, p. 7485 - 7488 (2007/10/02)
Treatment of 5'-chloro-5'-deoxynucleosides (5) with the conjugate base of 9-(4-methoxyphenyl)xanthen-9-thiol (3b), followed by acid-promoted removal of the 5'-S- group in the presence of pyrrole gives the corresponding 5'-deoxy-5'-mercaptonucleosides (7) in good yields.
