197504-84-0Relevant articles and documents
ACRIDINE DERIVATIVES WITH ANTITUMORAL ACTIVITY
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Page/Page column 7, (2008/06/13)
The present invention discloses new acridine derivatives according to general formula (I) below, useful as antitumor agents, methods for its preparation as well as pharmaceutical compositions containing the same are also disclosed: (Formula I).
Synthesis and structure of substituted arylazo-imidazolidines and arylidenethiazolidines
Brandao,Rocha Filho,Chantegrel,Albuquerque,Ximenes,Galdino,Pitta,Perrissin,Luu-Duc
, p. 206 - 211 (2007/10/03)
Synthesis and physico-chemical properties of four 3-benzyl or 3-(4-chlorobenzyl)-4-thioxo-5-arylazo-imidazolidin-2-ones, five 3-(4-nitrobenzyl)-5-arylidenethiazolidine-2,4-diones and three 3-(4-phenyl-phenacyl)-4-thioxo-5-arylidenethiazolidin-2-ones have been described. These new products were synthesized by an aldolisation-crotonisation reaction from aromatic aldehydes and 3-substituted thioxothiazolidin-2-ones or thiazolidine-2,4-diones. The arylazo-imidazolidine compounds were synthesized by copulation of diazonium ions with imidazolidines. Antimicrobial activity was determined for some compounds.