1977-11-3 Usage
Uses
Different sources of media describe the Uses of 1977-11-3 differently. You can refer to the following data:
1. Perlapine is an atypical neuroleptic that blocks dopamine and serotonin (5-HT) receptors (Kis = 60, 30, and 30 nM for D2, D4, and 5-HT2A, respectively). Perlapine is also an agonist for hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor that activates neuronal firing. Perlapine displays >10,000-fold selectivity for hM3Dq over hM3.
2. Perlapine exhibits antipsychotic activity and blocks dopamine and serotonin receptors. Perlapine is also a novel agonist of hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD).
Check Digit Verification of cas no
The CAS Registry Mumber 1977-11-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1977-11:
(6*1)+(5*9)+(4*7)+(3*7)+(2*1)+(1*1)=103
103 % 10 = 3
So 1977-11-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3
1977-11-3Relevant articles and documents
PESTICIDAL DIBENZO(HETERO)AZEPINE DERIVATIVES
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Page 75, (2010/02/07)
Use of compounds of formula (I): wherein X is S, O, S=O, SO2, NRa, or CRbRc;R1,R2 are halogen, OH, SH, NH2, CN, NO2, alkyl, alkoxy, alkylamino, dialkylamino, alkylthio
