1985-21-3 Usage
Description
Adenylyl-(3'-5')-uridine 3'-monophosphate, also known as cyclic AMP or cAMP, is a nucleic acid sequence that plays a crucial role in cellular signal transduction. It is a secondary messenger involved in various biological processes, including cell proliferation, metabolism, and immune responses. Its unique structure allows it to transmit signals within cells, making it a versatile molecule with potential applications in various fields.
Uses
Used in Pharmaceutical Development:
Adenylyl-(3'-5')-uridine 3'-monophosphate is used as a key molecule in the development of pharmaceuticals for various reasons. Its ability to regulate cellular processes makes it a promising candidate for the treatment of numerous diseases and conditions. By modulating the levels of cAMP within cells, it can potentially influence the activity of proteins and enzymes, leading to therapeutic effects.
Used in Biomedical Research:
In the field of biomedical research, adenylyl-(3'-5')-uridine 3'-monophosphate is used as a research tool to study the mechanisms of cellular signaling and regulation. Its involvement in various biological pathways makes it an essential molecule for understanding the complex interactions within cells and how they respond to external stimuli.
Used in Drug Delivery Systems:
Similar to gallotannin, adenylyl-(3'-5')-uridine 3'-monophosphate can also be incorporated into drug delivery systems to enhance its therapeutic potential. By using nanoparticles or other carriers, the delivery, bioavailability, and efficacy of cAMP can be improved, allowing for more targeted and effective treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 1985-21-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,8 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1985-21:
(6*1)+(5*9)+(4*8)+(3*5)+(2*2)+(1*1)=103
103 % 10 = 3
So 1985-21-3 is a valid CAS Registry Number.
1985-21-3Relevant articles and documents
Synthesis of a Dodecaribonucleotide, GUAUCAAUAAUG, by Use of "Fully" Protected Ribonucleotide Building Blocks
Kamimura, Takashi,Tsuchiya, Masahiko,Urakami, Ken-ichi,Koura, Koji,Sekine, Mitsuo,et al.
, p. 4552 - 4557 (2007/10/02)
The fully protected ribonucleotide monomer units (17, 19, 26, and 32) have been synthesized in excellent overall yields from unprotected ribonucleosides.Several carbamoyl groups were tested for protection of the guanosine base moiety.Finally, the diphenylcarbamoyl group was chosen and O6-(diphenylcarbamoyl)-N2-propionylguanosine was readily prepared in high yield and converted to the guanosine units 12 and 17.The uridine unit 19 was prepared by the acylation of the previous unit 18 with anisoyl chloride in the presence of i-Pr2EtN.In the case of the adenosine and cytidine units (26 and 32) , the regioselective 2'-O-tetrahydropyranylation was involved in their syntheses.These "perfectly" protected monomer units have succesfully been utilized in the synthesis of GUAUCAAUAAUG, a modified 5'-terminal structure, of brome mosic virus (BMV) mRNA no. 4 filament.The dodecamer chain was elongated by fragment condensation from the 3'-5' direction.The yields of the oligomer blocks have proved to be dramatically high because no side reactions occurred during the condensation reactions.Indeed, the final coupling to give the target 12-mer was achieved in 91percent yield.The deprotection of the fully protected in the usual manner gave GUAUCAAUAAUG in ca. 30percent yield.
Synthesis of dinucleotides in the ribose series with terminal 3'-phosphate groups
Rhaese,Siehr,Cramer
, p. 215 - 224 (2007/10/04)
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