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199594-65-5

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199594-65-5 Usage

Description

1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-4-methyl-1H-benzimidazole, also known as TAK-385, is a synthetic benzimidazole derivative with potent and selective antagonistic activity against the gonadotropin-releasing hormone (GnRH) receptor. This receptor plays a crucial role in the regulation of reproductive function, and TAK-385's ability to block it makes it a promising compound for various medical applications.

Uses

Used in Pharmaceutical Industry:
1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-4-methyl-1H-benzimidazole is used as a therapeutic agent for the treatment of hormone-sensitive cancers, such as prostate cancer and breast cancer. Its antagonistic action on the GnRH receptor helps in inhibiting the growth and progression of these cancers by disrupting hormonal signaling pathways.
Used in Endometriosis Treatment:
1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-4-methyl-1H-benzimidazole is used as a medical treatment for managing endometriosis, a condition where the tissue that normally lines the uterus grows outside of it, causing pain and discomfort. TAK-385's ability to block the GnRH receptor can help in reducing the hormonal imbalances associated with this condition.
Used in Uterine Fibroids Management:
1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-4-methyl-1H-benzimidazole is used as a treatment option for uterine fibroids, which are noncancerous growths in the uterus that can cause heavy bleeding and pain. By blocking the GnRH receptor, TAK-385 can help in reducing the size of these fibroids and alleviating the symptoms associated with them.
Further research is ongoing to explore the potential clinical applications of 1-(2,6-Difluorobenzyl)-2-(2,6-difluorophenyl)-4-methyl-1H-benzimidazole (TAK-385) in various medical fields, given its unique mechanism of action and potential therapeutic benefits.

Check Digit Verification of cas no

The CAS Registry Mumber 199594-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,9,5,9 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 199594-65:
(8*1)+(7*9)+(6*9)+(5*5)+(4*9)+(3*4)+(2*6)+(1*5)=215
215 % 10 = 5
So 199594-65-5 is a valid CAS Registry Number.

199594-65-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,6-difluorophenyl)-1-[(2,6-difluorophenyl)methyl]-4-methylbenzimidazole

1.2 Other means of identification

Product number -
Other names benzimidazole analogue,1

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:199594-65-5 SDS

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